7MFB
 
 | | Crystal structure of antibody 10E8v4 Fab - light chain H31F variant | | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | | Authors: | Kwon, Y.D, Kwong, P.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
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7MFA
 | | Crystal structure of antibody 10E8v4-P100fA+P100gA Fab | | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | | Authors: | Kwon, Y.D, Kwong, P.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
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7MF7
 | | Crystal structure of antibody 10E8v4-P100gA Fab | | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | | Authors: | Kwon, Y.D, Kwong, P.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
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7MF8
 | | Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422 | | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | | Authors: | Kwon, Y.D, Kwong, P.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
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7MF9
 | | Crystal structure of antibody 10E8v4-P100fA Fab in space group C2 | | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | | Authors: | Kwon, Y.D, Kwong, P.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
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7KQY
 | | Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies | | Descriptor: | Heavy-Chain only Human Antibodies | | Authors: | Bahmanjah, S, Mieczkowski, C, Yu, Y, Baker, J, Raghunathan, G, Tomazela, D, Hsieh, M, Mccoy, M, Strickland, C, Fayadat-Dilman, L. | | Deposit date: | 2020-11-18 | | Release date: | 2020-12-16 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.913 Å) | | Cite: | Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies.
Antibodies, 9, 2020
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6VRT
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9B75
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9B7B
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9B74
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9B76
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9I1Q
 | | HER3 receptor in complex with the Fab fragment of TK-hu A3 monoclonal antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-3, ... | | Authors: | Bulfaro, G, Savino, C, Costanzo, A, Fata, F, Vallone, B, Montemiglio, L.C. | | Deposit date: | 2025-01-16 | | Release date: | 2025-10-15 | | Last modified: | 2025-11-05 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Novel Humanized Anti-HER3 Antibodies: Structural Characterization and Therapeutic Activity.
Antibodies, 14, 2025
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5WKO
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8Q6K
 | | Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ... | | Authors: | Davies, A.M, Vester, S.K, McDonnell, J.M. | | Deposit date: | 2023-08-11 | | Release date: | 2023-12-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor.
Antibodies, 12, 2023
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7KFG
 | | Antibody Fab BDBV-289 | | Descriptor: | Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER | | Authors: | Murin, C.D, Bruhn, J.F, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.002 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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9FQO
 | | Crystal structure of C0083 Fab targeting the oxidized macrophage migration inhibitory factor (oxMIF) | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C0083 Fab heavy chain, C0083 Fab light chain | | Authors: | Rossmueller, G, Mirkina, I, Thiele, M, Puchol Tarazona, A.A, Rueker, F, Kerschbaumer, R.J, Schinagl, A. | | Deposit date: | 2024-06-17 | | Release date: | 2025-01-01 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Integrating In Silico and In Vitro Tools for Optimized Antibody Development-Design of Therapeutic Anti-oxMIF Antibodies.
Antibodies, 13, 2024
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8EQ6
 | | PD1 signaling receptor bound to FAB Complex | | Descriptor: | Antibody FAB heavy chain, Antibody FAB light chain, Programmed cell death protein 1 | | Authors: | Bjorkelid, C, Paluch, C, Robertson, N.J. | | Deposit date: | 2022-10-07 | | Release date: | 2023-10-11 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Immunity, 57, 2024
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5E94
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5LDN
 | | A viral capsid:antibody complex | | Descriptor: | Hexon protein,hexon capsid, antibody | | Authors: | James, L. | | Deposit date: | 2016-06-27 | | Release date: | 2017-07-12 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Antibody-antigen kinetics constrain intracellular humoral immunity.
Sci Rep, 6, 2016
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6OSV
 | | Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | | Descriptor: | Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 | | Authors: | Park, H, Rader, C. | | Deposit date: | 2019-05-02 | | Release date: | 2020-04-01 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
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6OSH
 | | Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | | Descriptor: | Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 | | Authors: | Park, H, Rader, C. | | Deposit date: | 2019-05-01 | | Release date: | 2020-04-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.117 Å) | | Cite: | Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
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1CFV
 | | MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI | | Descriptor: | ESTRONE BETA-D-GLUCURONIDE, MONOCLONAL ANTIBODY FV4155, ZINC ION | | Authors: | Trinh, C.H, Phillips, S.E.V. | | Deposit date: | 1997-04-11 | | Release date: | 1997-10-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity.
Structure, 5, 1997
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4QF1
 | | Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ... | | Authors: | Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F. | | Deposit date: | 2014-05-19 | | Release date: | 2015-02-18 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
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2AJV
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2AK1
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