9LY6

antibody 20G5 (Fab')2 in complex with human B7-H3

Summary for 9LY6

• Entry DOI: 10.2210/pdb9ly6/pdb
• EMDB information: 63505
• Descriptor: CD276 antigen, antibody 20G5 Fab heavy chain, antibody 20G5 Fab light chain (3 entities in total)
• Functional Keywords: b7-h3, antibody, complex, antitumor protein/immune system, antitumor protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 143681.53

Authors

Li, B.,Zhou, S.,He, K. (deposition date: 2025-02-19, release date: 2026-03-04)

• Primary citation: Bin, L.,Shuaixiang, Z.,Kaijie, H.; B7-H3-mediated cis-inhibition of EGFR by a tumor-selective bispecific antibody enhances anti-tumor efficacy and minimizes on-target toxicities; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.67 Å)