PDB: 1932 件ウェブページステータス検索Chemie searchBIRD

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2R93	Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Lehmann, E, Brueckner, F, Cramer, P. 登録日 2007-09-12 公開日 2007-11-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
2E9T	Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-01-26 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
4Y34	Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 分子名称: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... 著者 Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. 登録日 2015-02-10 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
6XD1	Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-640 分子名称: (2R)-4-(butyl{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}carbamoyl)-1-(2,2-diphenylpropanoyl)piperazine-2-carboxylic acid, RNA-dependent RNA polymerase, ZINC ION 著者 Arora, R, Benson, T.E, Liew, C.W, Lescar, J. 登録日 2020-06-09 公開日 2020-09-23 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94, 2020
6XD0	Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-434 分子名称: 2-[({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)amino]-2,3-dihydro-1H-indene-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Arora, R, Benson, T.E, Liew, C.W, Lescar, J. 登録日 2020-06-09 公開日 2020-09-23 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (2.012 Å) 主引用文献 Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94, 2020
6S2L	FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide 分子名称: GLYCEROL, Genome polyprotein 著者 Verdaguer, N, Ferrer-Orta, C. 登録日 2019-06-21 公開日 2019-07-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 (F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase. Molecules, 24, 2019
3OLA	Poliovirus polymerase elongation complex with 2'-deoxy-CTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL8	Poliovirus polymerase elongation complex with CTP-Mn 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
5I61	Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus 分子名称: Potential RNA-dependent RNA polymerase 著者 Collier, A.M, Guo, Y.R, Tao, Y.J. 登録日 2016-02-15 公開日 2016-03-16 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus 分子名称: Potential RNA-dependent RNA polymerase 著者 Collier, A.M, Guo, Y.R, Tao, Y.J. 登録日 2016-02-15 公開日 2016-03-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
3NAH	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase 分子名称: RNA dependent RNA polymerase, SULFATE ION 著者 Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. 登録日 2010-06-02 公開日 2011-06-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
3NAI	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase 分子名称: 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... 著者 Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. 登録日 2010-06-02 公開日 2011-06-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
3OL9	Poliovirus polymerase elongation complex with 3'-deoxy-CTP 分子名称: ISOPROPYL ALCOHOL, PYROPHOSPHATE 2-, Polymerase, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL7	Poliovirus polymerase elongation complex with CTP 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OLB	Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, Polymerase, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL6	Poliovirus polymerase elongation complex 分子名称: ISOPROPYL ALCOHOL, Polymerase, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*CP*GP*GP*AP*AP*A)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
5F3T	Dengue serotype 3 RNA-dependent RNA polymerase bound to JF-31-MG46 分子名称: 2-(4-methoxy-3-phenyl-phenyl)ethanoic acid, RNA-DEPENDENT RNA POLYMERASE, ZINC ION 著者 Noble, C.G. 登録日 2015-12-03 公開日 2016-02-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening. J.Biol.Chem., 291, 2016
5TSN	Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex 分子名称: MANGANESE (II) ION, Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3') 著者 Shaik, M.M, Ng, K.K. 登録日 2016-10-30 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences. Proteins, 85, 2017
2R70	Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus. 分子名称: INFECTIOUS BURSAL VIRUS VP1 POLYMERASE 著者 Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. 登録日 2007-09-07 公開日 2007-11-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Activation mechanism of a noncanonical RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.Usa, 104, 2007
2R72	Crystal structure of infectious bursal disease virus VP1 polymerase, incubated with Mg2+ ion. 分子名称: INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, MAGNESIUM ION 著者 Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. 登録日 2007-09-07 公開日 2007-11-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Activation mechanism of a noncanonical RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.Usa, 104, 2007
3N6N	crystal structure of EV71 RdRp in complex with Br-UTP 分子名称: 5-bromouridine 5'-(tetrahydrogen triphosphate), NICKEL (II) ION, RNA-dependent RNA polymerase 著者 Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H. 登録日 2010-05-26 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1, 2010
3N6M	Crystal structure of EV71 RdRp in complex with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase 著者 Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H. 登録日 2010-05-26 公開日 2011-06-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1, 2010
5Y6Z	Crystal structure of the coxsackievirus A16 polymerase elongation complex 分子名称: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... 著者 Bi, P, Shu, B, Gong, P. 登録日 2017-08-15 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics Virol Sin, 32, 2017
6TZ1	In situ structure of BmCPV RNA-dependent RNA polymerase at early-elongation state 分子名称: Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*A)-3'), RNA-dependent RNA Polymerase, Template RNA (5'-R(P*AP*GP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... 著者 Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. 登録日 2019-08-09 公開日 2019-11-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
6TZ2	In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-template RNA (36-MER), ... 著者 Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. 登録日 2019-08-09 公開日 2019-11-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019

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