PDB: 1391 resultsInfo pagesStatus searchChemie searchBIRD

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5B8C	High resolution structure of the human PD-1 in complex with pembrolizumab Fv Descriptor: Pembrolizumab heavy chain variable region (PemVH), Pembrolizumab light chain variable region (PemVL), Programmed cell death protein 1 Authors: Horita, S, Shimamura, T, Iwata, S, Nomura, N. Deposit date: 2016-06-14 Release date: 2016-10-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.146 Å) Cite: High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1 Sci Rep, 6, 2016
5AYQ	Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of VGSC beta subunits Descriptor: Sodium channel subunit beta-4 Authors: Shimizu, H. Deposit date: 2015-09-01 Release date: 2016-06-08 Last modified: 2020-02-19 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel beta subunits Sci Rep, 6, 2016
5B21	Dimer structure of murine Nectin-1 D1 Descriptor: murine Nectin-1 D1 Authors: Sangawa, T, Takebe, K, Suzuki, M. Deposit date: 2015-12-28 Release date: 2016-12-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Dimer structure of murine Nectin-1 D1 To Be Published
5C9K	Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2 Descriptor: ACETATE ION, Amyloid lambda 6 light chain variable region PIP Authors: Hernandez-Santoyo, A, Rodriguez-Romero, A, Luna-Martinez, O.D, Becerril-Lujan, B. Deposit date: 2015-06-27 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Mutating amyloidogenic lambda6 light chain AR back to germline 6aJL2 To Be Published
5C6W	anti-CXCL13 scFv - E10 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Tu, C, Bard, J, Mosyak, L. Deposit date: 2015-06-23 Release date: 2015-11-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair To Be Published
5C2B	anti-CXCL13 parental scFv - 3B4 Descriptor: CHLORIDE ION, scFv 3B4 Authors: Tu, C, Bard, J, Mosyak, L. Deposit date: 2015-06-15 Release date: 2015-11-04 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (1.4049 Å) Cite: Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair To Be Published
5C3T	PD-1 binding domain from human PD-L1 Descriptor: Programmed cell death 1 ligand 1 Authors: Zak, K.M, Dubin, G, Holak, T.A. Deposit date: 2015-06-17 Release date: 2015-11-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1. Structure, 23, 2015
5D4K	Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polymeric immunoglobulin receptor, SULFATE ION, ... Authors: Stadtmueller, B.M, Bjorkman, P.J. Deposit date: 2015-08-07 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.599 Å) Cite: The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife, 5, 2016
5E5M	Crystal structure of mouse CTLA-4 in complex with nanobody Descriptor: CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, GLYCEROL Authors: Fedorov, A.A, Fedorov, E.V, Samanta, D, Bonanno, J.B, Almo, S.C. Deposit date: 2015-10-08 Release date: 2016-10-12 Last modified: 2019-01-30 Method: X-RAY DIFFRACTION (2.182 Å) Cite: Crystal structure of mouse CTLA-4 in complex with nanobody To Be Published
5EBG	Crystal structure of bovine CD8aa homodimer Descriptor: T-cell surface glycoprotein CD8 alpha chain Authors: Liu, Y, Li, X, Zhang, N, Qi, J, Xia, C. Deposit date: 2015-10-19 Release date: 2016-09-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
5DZN	human T-cell immunoglobulin and mucin domain protein 4 Descriptor: T-cell immunoglobulin and mucin domain-containing protein 4 Authors: Yuan, S, Rao, Z, Wang, X. Deposit date: 2015-09-25 Release date: 2015-11-25 Last modified: 2016-02-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope. Protein Cell, 6, 2015
5DZL	Crystal structure of the protein human CEACAM1 Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1 Authors: Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. Deposit date: 2015-09-25 Release date: 2015-10-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.4006 Å) Cite: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
5E56	Crystal structure of mouse CTLA-4 Descriptor: Cytotoxic T-lymphocyte protein 4, SODIUM ION Authors: Fedorov, A.A, Fedorov, E.V, SAMANTA, D, Bonanno, J.B, Almo, S.C. Deposit date: 2015-10-07 Release date: 2015-10-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.504 Å) Cite: Crystal structure of mouse CTLA-4 To Be Published
5EB9	Crystal Structure Of Chicken CD8aa Homodimer Descriptor: CD8 alpha chain Authors: Liu, Y.J, Qi, J.X, Xia, C. Deposit date: 2015-10-18 Release date: 2016-09-14 Method: X-RAY DIFFRACTION (2.006 Å) Cite: The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
5DZO	Crystal structure of human T-cell immunoglobulin and mucin domain protein 1 Descriptor: Hepatitis A virus cellular receptor 1, NITRATE ION, SODIUM ION Authors: Yuan, S, Rao, Z, Wang, X. Deposit date: 2015-09-25 Release date: 2015-11-25 Last modified: 2016-02-10 Method: X-RAY DIFFRACTION (1.301 Å) Cite: TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope. Protein Cell, 6, 2015
5EDX	Crystal structure of swine CD8aa homodimer Descriptor: CD8 alpha antigen Authors: Liu, Y.J, Qi, J.X, Zhang, N.Z, Xia, C. Deposit date: 2015-10-22 Release date: 2016-09-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.801 Å) Cite: The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
5ELI	Triggering receptor expressed on myeloid cells 2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Triggering receptor expressed on myeloid cells 2 Authors: Brett, T.J, Kober, D.L. Deposit date: 2015-11-04 Release date: 2016-12-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.0977 Å) Cite: Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. Elife, 5, 2016
5F1S	Crystal structure of the teleost fish polymeric Ig receptor (pIgR) ectodomain Descriptor: polymeric Immunoglobulin Receptor Authors: Stadtmueller, B.M, Bjorkman, P.J. Deposit date: 2015-11-30 Release date: 2016-03-16 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (1.749 Å) Cite: The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife, 5, 2016
5F71	Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3) Descriptor: Hepatitis A virus cellular receptor 2, SODIUM ION Authors: Gao, G.F, Lu, G, Wang, H, Qi, J. Deposit date: 2015-12-07 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.404 Å) Cite: Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5F70	Crystal structures of human TIM members Descriptor: Hepatitis A virus cellular receptor 1 Authors: Gao, G.F, Lu, G, Wang, H, Qi, J. Deposit date: 2015-12-07 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5F7F	Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) Descriptor: T-cell immunoglobulin and mucin domain-containing protein 4 Authors: Gao, G.F, Lu, G, Wang, H, Qi, J. Deposit date: 2015-12-08 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.502 Å) Cite: Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5FEB	Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain Descriptor: GLYCEROL, Sodium channel subunit beta-2 Authors: Das, S, Van Petegem, F. Deposit date: 2015-12-16 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Binary architecture of the Nav1.2-beta 2 signaling complex. Elife, 5, 2016
5F7H	Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine Descriptor: CALCIUM ION, PHOSPHOSERINE, T-cell immunoglobulin and mucin domain-containing protein 4 Authors: Gao, G.F, Lu, G, Wang, H, Qi, J. Deposit date: 2015-12-08 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5FFL	Crystal structure of mouse CD300lf at 1.6 Angstroms resolution. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ... Authors: Nelson, C.A, Fremont, D.H. Deposit date: 2015-12-18 Release date: 2016-08-31 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Discovery of a proteinaceous cellular receptor for a norovirus. Science, 353, 2016
5FDY	Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain, C72A/C75A mutant Descriptor: GLYCEROL, Sodium channel subunit beta-2 Authors: Das, S, Van Petegem, F. Deposit date: 2015-12-16 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Binary architecture of the Nav1.2-beta 2 signaling complex. Elife, 5, 2016

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