5C2B

anti-CXCL13 parental scFv - 3B4

Summary for 5C2B

DescriptorscFv 3B4 heavy chain, 3B4 light chain, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsanti-cxcl13, scfv, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight26684.27
Authors
Tu, C.,Bard, J.,Mosyak, L. (deposition date: 2015-06-15, release date: 2015-11-04, Last modification date: 2017-11-01)
Primary citation
Tu, C.,Terrabube, V.,Tam, A.,Stochaj, W.,Fennell, B.,Lin, L.,Stahl, M.,LaVallie, E.,Somers, W.,Finlay, W.,Mosyak, L.,Bard, J.,Cunningham, O.
Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.4049 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.194301.5%6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5c2b
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Molmil generated image of 5c2b
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Molmil generated image of 5c2b
rotated about y axis by 90°