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7TUG	Crystal structure of Tapasin in complex with PaSta2-Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta2 Fab heavy chain, PaSta2 Fab kappa light chain, ... Authors: Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H. Deposit date: 2022-02-02 Release date: 2022-09-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
7TUF	Crystal structure of Tapasin in complex with PaSta1-Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta1 Fab heavy chain, PaSta1 Fab kappa light chain, ... Authors: Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H. Deposit date: 2022-02-02 Release date: 2022-09-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
5IQ7	Crystal structure of 10E8-S74W Fab in complex with an HIV-1 gp41 peptide. Descriptor: 10E8-S74W Heavy Chain, 10E8-S74W Light Chain, gp41 MPER peptide Authors: Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D. Deposit date: 2016-03-10 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2869 Å) Cite: Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. J.Virol., 90, 2016
5IQ9	Crystal structure of 10E8v4 Fab in complex with an HIV-1 gp41 peptide. Descriptor: 10E8v4 Heavy Chain, 10E8v4 Light Chain, gp41 MPER peptide Authors: Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D. Deposit date: 2016-03-10 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. J.Virol., 90, 2016
5JII	Crystal structure of human IgG1-Fc Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... Authors: Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. Deposit date: 2016-04-22 Release date: 2017-04-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
5IW3	anti-CD20 monoclonal antibody Fc fragment Descriptor: ACETATE ION, Ig gamma-1 chain C region, SULFATE ION, ... Authors: Tang, C, Chen, Z. Deposit date: 2016-03-21 Release date: 2017-03-29 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of anti-CD20 monoclonal antibody Fc fragment at 2.05 Angstroms resolution To Be Published
5IW6	anti-CD20 monoclonal antibody Fc fragment Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Tang, C, Chen, Z. Deposit date: 2016-03-22 Release date: 2017-03-29 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structure of anti-CD20 monoclonal antibody Fc fragment at 2.34 Angstroms resolution To Be Published
5JIK	Crystal structure of HER2 binding IgG1-Fc (Fcab H10-03-6) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. Deposit date: 2016-04-22 Release date: 2017-04-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
2CK0	ANTI-ANTI-IDIOTYPIC ANTIBODY AGAINST HUMAN ANGIOTENSIN II, COMPLEX WITH A SYNTHETIC CYCLIC PEPTIDE Descriptor: PROTEIN (11-MER; CYCLIC PEPTIDE), PROTEIN (IMMUNOGLOBULIN; HEAVY CHAIN), PROTEIN (IMMUNOGLOBULIN; LIGHT CHAIN) Authors: Pan, Y.H, Amzel, L.M. Deposit date: 1999-06-13 Release date: 2003-08-05 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of Angiotensin II and a Phage-Display Selected Cyclic Peptide in Complex with Fab131: Making Angiotensin II Analogs To be Published
2CDE	Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR Descriptor: INKT-TCR Authors: Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y. Deposit date: 2006-01-23 Release date: 2006-03-07 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors J.Exp.Med., 203, 2006
2D4F	The Crystal Structure of human beta2-microglobulin Descriptor: Beta-2-microglobulin, SODIUM ION Authors: Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. Deposit date: 2005-10-18 Release date: 2006-08-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis J.Biol.Chem., 281, 2006
2D4D	The Crystal Structure of human beta2-microglobulin, L39W W60F W95F Mutant Descriptor: Beta-2-microglobulin, SODIUM ION Authors: Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. Deposit date: 2005-10-17 Release date: 2006-08-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis J.Biol.Chem., 281, 2006
2DBL	MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY Descriptor: 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN) Authors: Arevalo, J.H, Wilson, I.A. Deposit date: 1994-02-08 Release date: 1994-03-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. Nature, 365, 1993
2DTS	Crystal Structure of the Defucosylated Fc Fragment from Human Immunoglobulin G1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region Authors: Matsumiya, S, Yamaguchi, Y, Saito, J, Nagano, M, Sasakawa, H, Otaki, S, Satoh, M, Shitara, K, Kato, K. Deposit date: 2006-07-14 Release date: 2007-03-13 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural comparison of fucosylated and nonfucosylated fc fragments of human immunoglobulin g1 J.Mol.Biol., 368, 2007
2F8O	A Native to Amyloidogenic Transition Regulated by a Backbone Trigger Descriptor: Beta-2-microglobulin Authors: Eakin, C.M, Berman, A.J, Miranker, A.D. Deposit date: 2005-12-02 Release date: 2006-02-21 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A native to amyloidogenic transition regulated by a backbone trigger. Nat.Struct.Mol.Biol., 13, 2006
2F19	THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY Descriptor: IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN) Authors: Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A. Deposit date: 1992-05-27 Release date: 1992-10-15 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. Proc.Natl.Acad.Sci.USA, 89, 1992
1A3L	CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION Descriptor: 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN) Authors: Heine, A, Wilson, I.A. Deposit date: 1998-01-22 Release date: 1999-02-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.95 Å) Cite: An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. Science, 279, 1998
3IB4	The double mutant of Beta-2 microglobulin K58P-W60G Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin Authors: Colombo, M, Ricagno, S, Bolognesi, M. Deposit date: 2009-07-15 Release date: 2010-07-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Crystal structure of the Beta-2 microglobulin mutant K58P-W60G To be Published
1AI1	HIV-1 V3 LOOP MIMIC Descriptor: AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN) Authors: Ghiara, J.B, Wilson, I.A. Deposit date: 1996-11-06 Release date: 1997-05-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J.Mol.Biol., 266, 1997
1AIF	ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB FROM MOUSE Descriptor: ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (HEAVY CHAIN), ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (LIGHT CHAIN) Authors: Ban, N, Escobar, C, Hasel, K, Day, J, Greenwood, A, McPherson, A. Deposit date: 1994-11-14 Release date: 1997-02-01 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of an anti-idiotypic Fab against feline peritonitis virus-neutralizing antibody and a comparison with the complexed Fab. FASEB J., 9, 1995
1ADQ	CRYSTAL STRUCTURE OF A HUMAN IGM RHEUMATOID FACTOR FAB IN COMPLEX WITH ITS AUTOANTIGEN IGG FC Descriptor: IGG4 REA FC, IGM-LAMBDA RF-AN FAB (HEAVY CHAIN), IGM-LAMBDA RF-AN FAB (LIGHT CHAIN) Authors: Corper, A.L, Taussig, M.J, Sutton, B.J. Deposit date: 1997-02-18 Release date: 1998-09-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction. Nat.Struct.Biol., 4, 1997
1AJ7	IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY Descriptor: 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN) Authors: Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. Deposit date: 1997-05-15 Release date: 1997-11-12 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insights into the evolution of an antibody combining site. Science, 276, 1997
1A4J	DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR Descriptor: IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) Authors: Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. Deposit date: 1998-01-30 Release date: 1998-05-13 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
1A0Q	29G11 COMPLEXED WITH PHENYL [1-(1-N-SUCCINYLAMINO)PENTYL] PHOSPHONATE Descriptor: 29G11 FAB (HEAVY CHAIN), 29G11 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE, ... Authors: Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J. Deposit date: 1997-12-05 Release date: 1999-03-02 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A comparison of the crystallographic structures of two catalytic antibodies with esterase activity. J.Mol.Biol., 282, 1998
15C8	CATALYTIC ANTIBODY 5C8, FREE FAB Descriptor: IGG 5C8 FAB (HEAVY CHAIN), IGG 5C8 FAB (LIGHT CHAIN) Authors: Gruber, K, Wilson, I.A. Deposit date: 1998-03-18 Release date: 1999-03-23 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Ligand-Induced Conformational Changes in a Catalytic Antibody: Comparison of the Bound and Unbound Structure of Fab 5C8 To be Published

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