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6WOX	Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2020-04-26 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.14 Å) Cite: The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
5VI8	Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... Authors: Hubin, E.A, Campbell, E.A, Darst, S.A. Deposit date: 2017-04-14 Release date: 2017-04-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
7XL4	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: He, D.W, You, L.L, Zhang, Y. Deposit date: 2022-04-21 Release date: 2022-07-27 Last modified: 2023-02-08 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XL3	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: He, D.W, You, L.L, Zhang, Y. Deposit date: 2022-04-21 Release date: 2022-07-27 Last modified: 2022-08-03 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7X76	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, X, Zheng, J. Deposit date: 2022-03-09 Release date: 2022-08-03 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
6WMU	E. coli RNAPs70-SspA-gadA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WOY	Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2020-04-26 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3 Å) Cite: The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
5W1S	X-ray crystal structure of Escherichia coli RNA polymerase and TraR complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Murakami, K.S, Molodtsov, V. Deposit date: 2017-06-04 Release date: 2017-06-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.805 Å) Cite: Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
7BEG	Structures of class I bacterial transcription complexes Descriptor: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... Authors: Ye, F.Z, Hao, M, Zhang, X.D. Deposit date: 2020-12-23 Release date: 2021-12-01 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
7BEF	Structures of class II bacterial transcription complexes Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hao, M, Ye, F.Z, Zhang, X.D. Deposit date: 2020-12-23 Release date: 2021-12-01 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
5W1T	X-ray crystal structure of Escherichia coli RNA polymerase and DksA complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Murakami, K.S, Molodtsov, V. Deposit date: 2017-06-04 Release date: 2017-06-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (4.5 Å) Cite: Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
7CKQ	The cryo-EM structure of B. subtilis BmrR transcription activation complex Descriptor: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Fang, C.L, Zhang, Y. Deposit date: 2020-07-18 Release date: 2020-12-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription. Nat Commun, 11, 2020
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA Descriptor: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lin, W, Feng, Y. Deposit date: 2020-06-05 Release date: 2020-08-12 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
5X21	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) Descriptor: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zhang, Y, Ebright, R. Deposit date: 2017-01-29 Release date: 2017-07-05 Last modified: 2022-10-12 Method: X-RAY DIFFRACTION (3.323 Å) Cite: Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
5X22	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zhang, Y, Ebright, R. Deposit date: 2017-01-29 Release date: 2017-07-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lin, W, Feng, Y. Deposit date: 2020-07-06 Release date: 2020-08-12 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
6XL9	Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Yang, Y, Liu, C, Shi, W, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLJ	Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt) Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLM	Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription Descriptor: 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XL5	Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo) Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLL	Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt) Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XH7	CueR-TAC without RNA Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W, Yang, Y. Deposit date: 2020-06-18 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
6XH8	CueR-transcription activation complex with RNA transcript Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W, Yang, Y. Deposit date: 2020-06-18 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
7XYA	The cryo-EM structure of an AlpA-loading complex Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Wen, A, Feng, Y. Deposit date: 2022-06-01 Release date: 2022-07-20 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022

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