PDB: 131 件ウェブページステータス検索Chemie searchBIRD

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6XI9	X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine 分子名称: 9-[7-(3-carboxyphenyl)-5,6-dideoxy-beta-D-ribo-heptodialdo-1,4-furanosyl]-9H-purin-6-amine, Aminodeoxyfutalosine synthase, CHLORIDE ION, ... 著者 Grove, T.L, Bonanno, J.B, Almo, S.C. 登録日 2020-06-19 公開日 2020-07-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis. Biochemistry, 59, 2020
6WTF	Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound 分子名称: COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ... 著者 Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J. 登録日 2020-05-02 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural basis for non-radical catalysis by TsrM, a radical SAM methylase. Nat.Chem.Biol., 17, 2021
6WTE	Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with cobalamin and [4Fe-4S] cluster bound 分子名称: 1,2-ETHANEDIOL, B12-binding domain-containing protein, COBALAMIN, ... 著者 Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J. 登録日 2020-05-02 公開日 2020-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structural basis for non-radical catalysis by TsrM, a radical SAM methylase. Nat.Chem.Biol., 17, 2021
6QK7	Elongator catalytic subcomplex Elp123 lobe 分子名称: 5'-DEOXYADENOSINE, Elongator complex protein 1, Elongator complex protein 2, ... 著者 Dauden, M.I, Jaciuk, M, Glatt, S. 登録日 2019-01-28 公開日 2019-07-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular basis of tRNA recognition by the Elongator complex. Sci Adv, 5, 2019
6Q2Q	Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, IRON/SULFUR CLUSTER, ... 著者 Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. 登録日 2019-08-08 公開日 2020-01-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.892 Å) 主引用文献 Structural Basis of the Substrate Selectivity of Viperin. Biochemistry, 59, 2020
6Q2P	Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. 登録日 2019-08-08 公開日 2020-01-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.452 Å) 主引用文献 Structural Basis of the Substrate Selectivity of Viperin. Biochemistry, 59, 2020
6IAZ	The archaeal Methanocaldococcus infernus Elp3 with N-terminus deletion (1-46) 分子名称: Histone acetyltransferase, ELP3 family, SULFATE ION 著者 Lin, T.Y, Glatt, S. 登録日 2018-11-28 公開日 2019-02-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Nat Commun, 10, 2019
6IAD	Apo crystal structure of archaeal Methanocaldococcus infernus Elp3 (del1-54) 分子名称: Histone acetyltransferase, ELP3 family, SULFATE ION 著者 Lin, T.Y, Glatt, S. 登録日 2018-11-26 公開日 2019-02-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Nat Commun, 10, 2019
6IA8	Apo crystal structure of archaeal Methanocaldococcus infernus Elp3 (del1-19) 分子名称: Histone acetyltransferase, ELP3 family, SULFATE ION 著者 Lin, T.Y, Glatt, S. 登録日 2018-11-26 公開日 2019-02-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Nat Commun, 10, 2019
6IA6	Crystal structure of the bacterial Dehalococcoides mccartyi Elp3 with desulfo-CoA 分子名称: DESULFO-COENZYME A, ELP3 family, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Lin, T.Y, Glatt, S. 登録日 2018-11-26 公開日 2019-02-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Nat Commun, 10, 2019
6FZ6	Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus 分子名称: BROMIDE ION, GLYCEROL, IRON/SULFUR CLUSTER, ... 著者 Hinchliffe, P, Shaw, J.M, Spencer, J. 登録日 2018-03-14 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus To Be Published
6FD2	Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine 分子名称: 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... 著者 Liu, W.Q, Amara, P, Mouesca, J.M, Ji, X, Renoux, O, Martin, L, Zhang, C, Zhang, Q, Nicolet, Y. 登録日 2017-12-21 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility. J. Am. Chem. Soc., 140, 2018
6EFN	Structure of a RiPP maturase, SkfB 分子名称: FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... 著者 Grell, T.A.J, Drennan, C.L. 登録日 2018-08-16 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.291 Å) 主引用文献 Structure of a RiPP maturase, SkfB J.Biol.Chem., 2018
6DJT	Structure of TYW1 with a lysine-pyruvate adduct bound 分子名称: DI(HYDROXYETHYL)ETHER, FE2/S3 CLUSTER, GLYCEROL, ... 著者 Grell, T.A.J, Drennan, C.L. 登録日 2018-05-26 公開日 2018-06-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1. J. Am. Chem. Soc., 140, 2018
6C8V	X-ray structure of PqqE from Methylobacterium extorquens 分子名称: Coenzyme PQQ synthesis protein E, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER 著者 Gizzi, A.S, Grove, T.L, Bonanno, J.B, Almo, S.C. 登録日 2018-01-25 公開日 2018-02-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE. Biochemistry, 57, 2018
6B4C	Structure of Viperin from Trichoderma virens 分子名称: CITRATE ANION, SULFATE ION, Viperin 著者 Huang, R.H, Selvadurai, K. 登録日 2017-09-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.795 Å) 主引用文献 Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin. J.Biol.Chem., 293, 2018
5WHY	Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides 分子名称: CALCIUM ION, IRON/SULFUR CLUSTER, Radical SAM domain protein, ... 著者 Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. 登録日 2017-07-18 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.692 Å) 主引用文献 Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides. J. Am. Chem. Soc., 139, 2017
5WGG	Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides 分子名称: CALCIUM ION, CteA, IRON/SULFUR CLUSTER, ... 著者 Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. 登録日 2017-07-14 公開日 2017-07-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.036 Å) 主引用文献 Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides. J. Am. Chem. Soc., 139, 2017
5VSM	Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine 分子名称: 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... 著者 Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. 登録日 2017-05-11 公開日 2017-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of viperin, an antiviral radical SAM enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VSL	Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH) 分子名称: IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE 著者 Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. 登録日 2017-05-11 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.972 Å) 主引用文献 Structural studies of viperin, an antiviral radical SAM enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1T	Crystal structure of Streptococcus suis SuiB bound to precursor peptide SuiA 分子名称: IRON/SULFUR CLUSTER, METHIONINE, Radical SAM, ... 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1S	Crystal structure of Streptococcus suis SuiB bound to S-adenosylmethionine 分子名称: IRON/SULFUR CLUSTER, Radical SAM, S-ADENOSYLMETHIONINE 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1Q	Crystal structure of Streptococcus suis SuiB 分子名称: IRON/SULFUR CLUSTER, Radical SAM 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UL4	Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin and S-adenosylmethionine bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALAMIN, ... 著者 Bridwell-Rabb, J, Drennan, C.L. 登録日 2017-01-24 公開日 2017-04-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis. Nature, 544, 2017
5UL3	Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin bound 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Bridwell-Rabb, J, Drennan, C.L. 登録日 2017-01-24 公開日 2017-04-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis. Nature, 544, 2017

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