PDB: 131 件ウェブページステータス検索Chemie searchBIRD

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6XI9	X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine 分子名称: 9-[7-(3-carboxyphenyl)-5,6-dideoxy-beta-D-ribo-heptodialdo-1,4-furanosyl]-9H-purin-6-amine, Aminodeoxyfutalosine synthase, CHLORIDE ION, ... 著者 Grove, T.L, Bonanno, J.B, Almo, S.C. 登録日 2020-06-19 公開日 2020-07-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis. Biochemistry, 59, 2020
6IA6	Crystal structure of the bacterial Dehalococcoides mccartyi Elp3 with desulfo-CoA 分子名称: DESULFO-COENZYME A, ELP3 family, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Lin, T.Y, Glatt, S. 登録日 2018-11-26 公開日 2019-02-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Nat Commun, 10, 2019
2YX0	Crystal structure of P. horikoshii TYW1 分子名称: radical sam enzyme 著者 Goto-Ito, S, Ishii, R, Ito, T, Shibata, R, Fusatomi, E, Sekine, S, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-23 公開日 2007-10-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis Acta Crystallogr.,Sect.D, 63, 2007
2Z2U	Crystal structure of archaeal TYW1 分子名称: UPF0026 protein MJ0257 著者 Suzuki, Y, Ishitani, R, Nureki, O. 登録日 2007-05-28 公開日 2007-10-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Radical SAM Enzyme Catalyzing Tricyclic Modified Base Formation in tRNA J.Mol.Biol., 372, 2007
3CB8	4Fe-4S-Pyruvate formate-lyase activating enzyme in complex with AdoMet and a peptide substrate 分子名称: FORMIC ACID, IRON/SULFUR CLUSTER, Pyruvate formate-lyase 1-activating enzyme, ... 著者 Vey, J.L, Drennan, C.L. 登録日 2008-02-21 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme. Proc.Natl.Acad.Sci.Usa, 105, 2008
3C8F	4Fe-4S-Pyruvate formate-lyase Activating Enzyme with partially disordered AdoMet 分子名称: IRON/SULFUR CLUSTER, Pyruvate formate-lyase 1-activating enzyme, TRIETHYLENE GLYCOL, ... 著者 Vey, J.L, Drennan, C.L. 登録日 2008-02-11 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme. Proc.Natl.Acad.Sci.Usa, 105, 2008
8AI4	Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 5 bound 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Polsinelli, I, Fyfe, C.D, Legrand, P, Kubiak, X, Chavas, L.M.G, Berteau, O, Benjdia, A. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8AI5	Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 6 bound 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... 著者 Polsinelli, I, Fyfe, C.D, Legrand, P, Kubiak, X, Chavas, L.M.G, Berteau, O, Benjdia, A. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8AI1	Crystal structure of radical SAM epimerase EpeE from Bacillus subtilis with [4Fe-4S] clusters and S-adenosyl-L-homocysteine bound. 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... 著者 Kubiak, X, Polsinelli, I, Chavas, L.M.G, Legrand, P, Fyfe, C.D, Benjdia, A, Berteau, O. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8AI2	Crystal structure of radical SAM epimerase EpeE from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 5 bound 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... 著者 Polsinelli, I, Fyfe, C.D, Legrand, P, Kubiak, X, Chavas, L.M.G, Berteau, O, Benjdia, A. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8AI6	Crystal structure of radical SAM epimerase EpeE D210A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and persulfurated cysteine bound 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... 著者 Polsinelli, I, Legrand, P, Fyfe, C.D, Benjdia, A, Berteau, O. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8AI3	Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters and S-adenosyl-L-methionine bound 分子名称: 1,2-ETHANEDIOL, GLYCEROL, IRON/SULFUR CLUSTER, ... 著者 Kubiak, X, Chavas, L.M.G, Legrand, P, Polsinelli, I, Fyfe, C.D, Benjdia, A, Berteau, O. 登録日 2022-07-25 公開日 2024-01-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme. Nat.Chem.Biol., 20, 2024
8VDW	X-Ray Crystal Structure of the biotin synthase from V. parvula 分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Biotin synthase, Fe4 H S5, ... 著者 Lachowicz, J.C, Grove, T.L. 登録日 2023-12-18 公開日 2024-01-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.807 Å) 主引用文献 Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion. J.Am.Chem.Soc., 146, 2024
8VCW	X-Ray Crystal Structure of the biotin synthase from B. obeum 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Biotin synthase, ... 著者 Lachowicz, J.C, Grove, T.L. 登録日 2023-12-14 公開日 2024-01-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion. J.Am.Chem.Soc., 146, 2024
8VPO	X-Ray Crystal Structure of TigE from Paramaledivibacter caminithermalis 分子名称: GLYCEROL, IRON/SULFUR CLUSTER, Radical SAM core domain-containing protein 著者 Grove, T.L, Lachowicz, J.C, Zizola, C. 登録日 2024-01-16 公開日 2024-02-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases. Acs Chem.Biol., 19, 2024
5TGS	Crystal Structure of QueE from Bacillus subtilis with methionine bound 分子名称: 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... 著者 Grell, T.A.J, Dowling, D.P, Drennan, C.L. 登録日 2016-09-28 公開日 2017-01-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.548 Å) 主引用文献 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies. J. Am. Chem. Soc., 139, 2017
5TH5	Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound 分子名称: 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... 著者 Grell, T.A.J, Dowling, D.P, Drennan, C.L. 登録日 2016-09-29 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies. J. Am. Chem. Soc., 139, 2017
5V1Q	Crystal structure of Streptococcus suis SuiB 分子名称: IRON/SULFUR CLUSTER, Radical SAM 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1T	Crystal structure of Streptococcus suis SuiB bound to precursor peptide SuiA 分子名称: IRON/SULFUR CLUSTER, METHIONINE, Radical SAM, ... 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1S	Crystal structure of Streptococcus suis SuiB bound to S-adenosylmethionine 分子名称: IRON/SULFUR CLUSTER, Radical SAM, S-ADENOSYLMETHIONINE 著者 Davis, K.M, Bacik, J.P, Ando, N. 登録日 2017-03-02 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VSM	Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine 分子名称: 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... 著者 Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. 登録日 2017-05-11 公開日 2017-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of viperin, an antiviral radical SAM enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VSL	Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH) 分子名称: IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE 著者 Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. 登録日 2017-05-11 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.972 Å) 主引用文献 Structural studies of viperin, an antiviral radical SAM enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WGG	Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides 分子名称: CALCIUM ION, CteA, IRON/SULFUR CLUSTER, ... 著者 Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. 登録日 2017-07-14 公開日 2017-07-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.036 Å) 主引用文献 Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides. J. Am. Chem. Soc., 139, 2017
5WHY	Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides 分子名称: CALCIUM ION, IRON/SULFUR CLUSTER, Radical SAM domain protein, ... 著者 Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. 登録日 2017-07-18 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.692 Å) 主引用文献 Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides. J. Am. Chem. Soc., 139, 2017
4K38	Native anSMEcpe with bound AdoMet and Kp18Cys peptide 分子名称: Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, GLYCEROL, ... 著者 Goldman, P.J, Drennan, C.L. 登録日 2013-04-10 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.831 Å) 主引用文献 X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification. Proc.Natl.Acad.Sci.USA, 110, 2013

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