4Fe-4S-Pyruvate formate-lyase Activating Enzyme with partially disordered AdoMet

Summary for 3C8F

DescriptorPyruvate formate-lyase 1-activating enzyme, IRON/SULFUR CLUSTER, [(3S)-3-amino-3-carboxypropyl](ethyl)methylsulfonium, ... (5 entities in total)
Functional Keywordsadomet radical, sam radical, activase, glycyl radical, carbohydrate metabolism, glucose metabolism, iron, iron-sulfur, metal-binding, oxidoreductase, s-adenosyl-l-methionine
Biological sourceEscherichia coli
Cellular locationCytoplasm P0A9N4
Total number of polymer chains1
Total molecular weight28795.25
Vey, J.L.,Drennan, C.L. (deposition date: 2008-02-11, release date: 2008-10-28, Last modification date: 2017-10-25)
Primary citation
Vey, J.L.,Yang, J.,Li, M.,Broderick, W.E.,Broderick, J.B.,Drennan, C.L.
Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Proc.Natl.Acad.Sci.Usa, 105:16137-16141, 2008
PubMed: 18852451 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0806640105
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.293221.2%3.9%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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