PDB: 107 件ウェブページステータス検索Chemie searchBIRD

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5MWW	Sigma1.1 domain of sigmaA from Bacillus subtilis 分子名称: RNA polymerase sigma factor SigA 著者 Zachrdla, M, Padrta, P, Rabatinova, A, Sanderova, H, Barvik, I, Krasny, L, Zidek, L. 登録日 2017-01-20 公開日 2017-06-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of domain 1.1 of the sigma (A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase core. J. Biol. Chem., 292, 2017
2K6X	Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure 分子名称: RNA polymerase sigma factor rpoD 著者 Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W. 登録日 2008-07-28 公開日 2008-10-28 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure Chem.Biol., 15, 2008
6CUX	Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (4.104 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
8U3B	Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A 分子名称: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Kompaniiets, D, Wang, D. 登録日 2023-09-07 公開日 2024-01-17 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Res., 52, 2024
8FTD	Structure of Escherichia coli CedA in complex with transcription initiation complex 分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, M, Vassyliev, N, Nudler, E. 登録日 2023-01-11 公開日 2024-01-10 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... 著者 Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. 登録日 2009-08-01 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (19.799999 Å) 主引用文献 Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
8IGR	Cryo-EM structure of CII-dependent transcription activation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. 登録日 2023-02-21 公開日 2023-05-17 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
8IGS	Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. 登録日 2023-02-21 公開日 2023-05-17 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
8JO2	Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA 分子名称: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... 著者 Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. 登録日 2023-06-06 公開日 2023-08-30 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
6VJS	Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex 分子名称: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2020-01-17 公開日 2020-10-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.02 Å) 主引用文献 Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice. Acs Infect Dis., 6, 2020
6WMT	F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.43 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMU	E. coli RNAPs70-SspA-gadA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017
6C9Y	Cryo-EM structure of E. coli RNAP sigma70 holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S. 登録日 2018-01-29 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.25 Å) 主引用文献 Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
6BYU	X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex 分子名称: (5R)-5-(6-amino-9H-purin-9-yl)-2-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-4-oxo-4,5-dihydrofuran-3-yl trihydrogen diphosphate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-12-21 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochim. Biophys. Acta, 1861, 2018
6CA0	Cryo-EM structure of E. coli RNAP sigma70 open complex 分子名称: DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ... 著者 Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S. 登録日 2018-01-29 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.75 Å) 主引用文献 Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
4JKR	Crystal Structure of E. coli RNA Polymerase in complex with ppGpp 分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, Wang, Y, Steitz, T.A. 登録日 2013-03-11 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex. Mol.Cell, 50, 2013
4JK1	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4JK2	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.201 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4KMU	X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S. 登録日 2013-05-08 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins. J.Med.Chem., 56, 2013
7MKJ	Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKE	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKI	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021

 

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