6AHO
| Crystal structure of Kap114p | Descriptor: | Importin subunit beta-5 | Authors: | Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C. | Deposit date: | 2018-08-20 | Release date: | 2019-10-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress. Embo Rep., 21, 2020
|
|
6KFT
| MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2019-07-08 | Release date: | 2020-07-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6A3B
| MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
5DH9
| |
6X2O
| Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1 | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... | Authors: | Baumhardt, J.M. | Deposit date: | 2020-05-20 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.551 Å) | Cite: | Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
|
|
7B51
| Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528 | Descriptor: | BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ... | Authors: | Shaikhqasem, A, Ficner, R. | Deposit date: | 2020-12-03 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77, 2021
|
|
1GCJ
| N-TERMINAL FRAGMENT OF IMPORTIN-BETA | Descriptor: | IMPORTIN BETA | Authors: | Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T. | Deposit date: | 2000-07-31 | Release date: | 2000-10-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. J.Mol.Biol., 302, 2000
|
|
3W5K
| Crystal structure of Snail1 and importin beta complex | Descriptor: | Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1 | Authors: | Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J. | Deposit date: | 2013-01-30 | Release date: | 2014-03-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta. Acta Crystallogr.,Sect.D, 70, 2014
|
|
2Z5K
| Complex of Transportin 1 with TAP NLS | Descriptor: | Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M. | Deposit date: | 2007-07-14 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
|
|
5ZPU
| LFS829 in complex with CRM1-Ran-RanBP1 | Descriptor: | (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ... | Authors: | Sun, Q, Lei, Y. | Deposit date: | 2018-04-16 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | To be published To Be Published
|
|
6A38
| MVM NS2 NES in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
4OO6
| Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) | Descriptor: | RNA-binding protein 39, Transportin-1 | Authors: | Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) | Deposit date: | 2014-01-30 | Release date: | 2014-02-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) to be published
|
|
7CYL
| |
6N1Z
| Importin-9 bound to H2A-H2B | Descriptor: | Histone H2A, Histone H2B 1.1, Importin-9 | Authors: | Tomchick, D.R, Chook, Y.M, Padavannil, A. | Deposit date: | 2018-11-12 | Release date: | 2019-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone. Elife, 8, 2019
|
|
6A3E
| MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
5VE8
| Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H3 1-28 | Descriptor: | Histone H3, Kap123 | Authors: | An, S, Yoon, J, Song, J.-J, Cho, U.-S. | Deposit date: | 2017-04-04 | Release date: | 2017-11-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123. Elife, 6, 2017
|
|
2BKU
| Kap95p:RanGTP complex | Descriptor: | GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ... | Authors: | Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M. | Deposit date: | 2005-02-21 | Release date: | 2005-05-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis for Nuclear Import Complex Dissociation by Rangtp Nature, 435, 2005
|
|
2XWU
| CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX | Descriptor: | IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9 | Authors: | Gruenwald, M, Bono, F. | Deposit date: | 2010-11-05 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation. Embo J., 30, 2011
|
|
1F59
| IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX | Descriptor: | FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1 | Authors: | Bayliss, R, Littlewood, T, Stewart, M. | Deposit date: | 2000-06-13 | Release date: | 2000-08-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell(Cambridge,Mass.), 102, 2000
|
|
1O6P
| |
1O6O
| |
3NBZ
| Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I) | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | Deposit date: | 2010-06-04 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
|
|
2X19
| Crystal structure of Importin13 - RanGTP complex | Descriptor: | GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ... | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | Deposit date: | 2009-12-23 | Release date: | 2010-02-16 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13. Mol.Cell, 37, 2010
|
|
4HB3
| |
6XJP
| |