PDB: 34 件ウェブページステータス検索Chemie searchBIRD

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1PMD	PENICILLIN-BINDING PROTEIN 2X (PBP-2X) 分子名称: PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME 著者 Pares, S, Mouz, N, Dideberg, O. 登録日 1996-02-05 公開日 1997-02-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme. Nat.Struct.Biol., 3, 1996
1QMF	PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX 分子名称: 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X 著者 Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. 登録日 1999-09-28 公開日 2000-05-25 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance J.Mol.Biol., 299, 2000
1QME	PENICILLIN-BINDING PROTEIN 2X (PBP-2X) 分子名称: PENICILLIN-BINDING PROTEIN 2X, SULFATE ION 著者 Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. 登録日 1999-09-28 公開日 2000-05-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance. J.Mol.Biol., 299, 2000
1K25	PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate 分子名称: low-affinity PENICILLIN-BINDING PROTEIN 2X 著者 Dessen, A, Mouz, N, Hopkins, J, Dideberg, O. 登録日 2001-09-26 公開日 2001-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations. J.Biol.Chem., 276, 2001
1PYY	Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-O-octanoyl-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, Penicillin-binding protein 2X, ... 著者 Chesnel, L, Pernot, L, Lemaire, D, Champelovier, D, Croize, J, Dideberg, O, Vernet, T, Zapun, A. 登録日 2003-07-09 公開日 2003-09-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains J.Biol.Chem., 278, 2003
1RP5	PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics 分子名称: SULFATE ION, penicillin-binding protein 2x 著者 Pernot, L, Chesnel, L, Legouellec, A, Croize, J, Vernet, T, Dideberg, O, Dessen, A. 登録日 2003-12-03 公開日 2004-02-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics. J.Biol.Chem., 279, 2004
2Z2M	Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae 分子名称: (2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, Penicillin-binding protein 2X, SULFATE ION 著者 Yamada, M, Watanabe, T, Takeuchi, Y. 登録日 2007-05-23 公開日 2007-09-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity Antimicrob.Agents Chemother., 51, 2007
2Z2L	Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae 分子名称: Penicillin-binding protein 2X, SULFATE ION 著者 Yamada, M, Watanabe, T, Takeuchi, Y. 登録日 2007-05-23 公開日 2007-09-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity Antimicrob.Agents Chemother., 51, 2007
2ZC4	Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae 分子名称: (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 2X, SULFATE ION 著者 Yamada, M, Watanabe, T, Takeuchi, Y. 登録日 2007-11-02 公開日 2008-04-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae Antimicrob.Agents Chemother., 52, 2008
2ZC3	Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae 分子名称: (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate, Penicillin-binding protein 2X, SULFATE ION 著者 Yamada, M, Watanabe, T, Takeuchi, Y. 登録日 2007-11-02 公開日 2008-04-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae Antimicrob.Agents Chemother., 52, 2008
2KUI	NMR structure of the PASTA domain of Mycobacterium tuberculosis of PknB 分子名称: Serine/threonine-protein kinase pknB 著者 Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M. 登録日 2010-02-17 公開日 2010-04-14 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation Structure, 18, 2010
2KUE	NMR structure of the PASTA domain 2 and 3 of Mycobacterium tuberculosis of PknB 分子名称: Serine/threonine-protein kinase pknB 著者 Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M. 登録日 2010-02-17 公開日 2010-04-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation Structure, 18, 2010
2KUF	NMR structure of the PASTA domain 3 and 4 of Mycobacterium tuberculosis of PknB 分子名称: Serine/threonine-protein kinase pknB 著者 Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M. 登録日 2010-02-17 公開日 2010-04-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation Structure, 18, 2010
2KUD	NMR structure of the PASTA domain 1 and 2 of Mycobacterium tuberculosis of PknB 分子名称: Serine/threonine-protein kinase pknB 著者 Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M. 登録日 2010-02-17 公開日 2010-04-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation Structure, 18, 2010
3M9G	Crystal structure of the three-PASTA-domain of a Ser/Thr kinase from Staphylococcus aureus 分子名称: Protein kinase, ZINC ION 著者 Paracuellos, P, Ballandras, A, Robert, X, Creze, C, Cozzone, A.J, Duclos, B, Gouet, P. 登録日 2010-03-22 公開日 2010-11-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Extended Conformation of the 2.9-A Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus J.Mol.Biol., 404, 2010
3OUV	SeMet Derivative of L512M mutant of PASTA domain 3 of Mycobacterium tuberculosis PknB 分子名称: Serine/threonine protein kinase 著者 Prigozhin, D.M, Chen, T.Y, Alber, T. 登録日 2010-09-15 公開日 2011-09-21 最終更新日 2016-12-14 実験手法 X-RAY DIFFRACTION (2.004 Å) 主引用文献 Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
3PY9	X-ray structural studies of the entire extra-cellular region of the Ser/Thr kinase PrkC from Staphylococcus aureus 分子名称: EUROPIUM ION, Protein kinase 著者 Ruggiero, A, Squeglia, F, Marasco, D, Marchetti, R, Molinaro, A, Berisio, R. 登録日 2010-12-12 公開日 2011-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus. Biochem.J., 435, 2011
2MGV	NMR structure of PASTA domain of PonA2 from Mycobacterium tuberculosis 分子名称: Bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 著者 Calvanese, L, Falcigno, L, Maglione, C, Marasco, D, Ruggiero, A, Squeglia, F, Berisio, R, D'Auria, G. 登録日 2013-11-11 公開日 2013-12-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis. Biopolymers, 101, 2014
5E12	Crystal Structure of PASTA Domains 2, 3 and 4 of Mycobacterium tuberculosis Protein Kinase B 分子名称: CITRATE ANION, Serine/threonine-protein kinase PknB 著者 Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC) 登録日 2015-09-29 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.208 Å) 主引用文献 Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
5E10	Crystal Structure of PASTA Domains 1 and 2 of Mycobacterium tuberculosis Protein Kinase B 分子名称: Serine/threonine-protein kinase PknB 著者 Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC) 登録日 2015-09-29 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
5E0Y	Crystal Structure of PASTA Domain 4 of Mycobacterium tuberculosis Protein Kinase B 分子名称: Serine/threonine-protein kinase PknB, ZINC ION 著者 Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC) 登録日 2015-09-29 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
5E0Z	Crystal Structure of PASTA Domains 3 and 4 of Mycobacterium tuberculosis Protein Kinase B 分子名称: Serine/threonine-protein kinase PknB 著者 Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC) 登録日 2015-09-29 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
5U47	1.95 Angstrom Resolution Crystal Structure of Penicillin Binding Protein 2X from Streptococcus thermophilus 分子名称: ACETATE ION, CHLORIDE ION, Penicillin binding protein 2X 著者 Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-12-03 公開日 2016-12-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 1.95 Angstrom Resolution Crystal Structure of Penicillin Binding Protein 2X from Streptococcus thermophilus. To Be Published
5NOD	PASTA subunit 4 of Streptococcus pneumoniae STKP crystallized with PEG and succinate 分子名称: Serine/threonine-protein kinase StkP 著者 Galisson, F, Gueguen-Chaignon, V, Gouet, P, Grangeasse, C, Zucchini, L. 登録日 2017-04-12 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 PASTA repeats of the protein kinase StkP interconnect cell constriction and separation of Streptococcus pneumoniae. Nat Microbiol, 3, 2018
5OAU	Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae 分子名称: Penicillin-binding protein 2X 著者 Bernardo-Garcia, N, Hermoso, J.A. 登録日 2017-06-23 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae. ACS Chem. Biol., 13, 2018

 

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