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2V0S
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crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
分子名称: GLYCEROL, LR1, MANGANESE (II) ION, ...
著者Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
登録日2007-05-17
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.
Nucleic Acids Res., 35, 2007
2JC5
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Apurinic Apyrimidinic (AP) endonuclease (NApe) from Neisseria Meningitidis
分子名称: 1,4-DIETHYLENE DIOXIDE, BICINE, EXODEOXYRIBONUCLEASE, ...
著者Carpenter, E.P, Corbett, A, Thomson, H, Adacha, J, Jensen, K, Bergeron, J, Kasampalidis, I, Exley, R, Winterbotham, M, Tang, C, Baldwin, G.S, Freemont, P.
登録日2006-12-19
公開日2007-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2JC4
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3'-5' exonuclease (NExo) from Neisseria Meningitidis
分子名称: ACETATE ION, DIHYDROGENPHOSPHATE ION, EXODEOXYRIBONUCLEASE III, ...
著者Carpenter, E.P, Corbett, A, Thomson, H, Adacha, J, Jensen, K, Bergeron, J, Kasampalidis, I, Exley, R, Winterbotham, M, Tang, C, Baldwin, G, Freemont, P.
登録日2006-12-19
公開日2007-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2ISI
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BU of 2isi by Molmil
Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand
分子名称: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, PHOSPHATE ION
著者Agarwal, R, Naidu, M.D.
登録日2006-10-17
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition
To be Published
2D1K
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BU of 2d1k by Molmil
Ternary complex of the WH2 domain of mim with actin-dnase I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Chereau, D, Kerff, F, Dominguez, R.
登録日2005-08-26
公開日2006-09-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the actin-binding function of missing-in-metastasis
Structure, 15, 2007
2F1N
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BU of 2f1n by Molmil
Structure of CdtB, the biologically active subunit of Cytolethal Distending Toxin
分子名称: Cytolethal distending toxin subunit B
著者Hontz, J.S, Yoder, M.D, Dreyfus, L.A.
登録日2005-11-14
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Differences in Crystal and Solution Structures of the Cytolethal Distending Toxin B Subunit: RELEVANCE TO NUCLEAR TRANSLOCATION AND FUNCTIONAL ACTIVATION.
J.Biol.Chem., 281, 2006
2DDT
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BU of 2ddt by Molmil
Crystal structure of sphingomyelinase from Bacillus cereus with magnesium ion
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ...
著者Ago, H, Oda, M, Tsuge, H, Katunuma, N, Miyano, M, Sakurai, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-02-02
公開日2006-05-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2DDS
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BU of 2dds by Molmil
Crystal structure of sphingomyelinase from Bacillus cereus with cobalt ion
分子名称: COBALT (II) ION, Sphingomyelin phosphodiesterase
著者Ago, H, Oda, M, Takahashi, M, Tsuge, H, Ochi, S, Katunuma, N, Miyano, M, Sakurai, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-02-02
公開日2006-05-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2DDR
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BU of 2ddr by Molmil
Crystal structure of sphingomyelinase from Bacillus cereus with calcium ion
分子名称: CALCIUM ION, Sphingomyelin phosphodiesterase
著者Ago, H, Oda, M, Takahashi, M, Tsuge, H, Ochi, S, Katunuma, N, Miyano, M, Sakurai, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-02-02
公開日2006-05-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2F2F
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BU of 2f2f by Molmil
Crystal structure of cytolethal distending toxin (CDT) from Actinobacillus actinomycetemcomitans
分子名称: Cytolethal distending toxin A, Cytolethal distending toxin B, cytolethal distending toxin C
著者Yamada, T, Komoto, J, Saiki, K, Konishi, K, Takusagawa, F.
登録日2005-11-16
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans
Protein Sci., 15, 2006
2A3Z
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Ternary complex of the WH2 domain of WASP with Actin-DNAse I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Chereau, D, Kerff, F, Dominguez, R.
登録日2005-06-27
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A40
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Ternary complex of the WH2 domain of WAVE with Actin-DNAse I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Chereau, D, Kerff, F, Dominguez, R.
登録日2005-06-27
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A41
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Ternary complex of the WH2 Domain of WIP with Actin-DNAse I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Chereau, D, Kerff, F, Dominguez, R.
登録日2005-06-27
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A42
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BU of 2a42 by Molmil
Actin-DNAse I Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Chereau, D, Kerff, F, Dominguez, R.
登録日2005-06-27
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZWX
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BU of 1zwx by Molmil
Crystal Structure of SmcL
分子名称: GLYCEROL, PHOSPHATE ION, sphingomyelinase-c
著者Openshaw, A.E.A, Race, P.R, Monzo, H.J, Vasquez-Boland, J.A, Banfield, M.J.
登録日2005-06-06
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria.
J.Biol.Chem., 280, 2005
1SR4
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BU of 1sr4 by Molmil
Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin
分子名称: BROMIDE ION, Cytolethal distending toxin subunit A, cytolethal distending toxin protein B, ...
著者Nesic, D, Hsu, Y, Stebbins, C.E.
登録日2004-03-22
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Assembly and Function of a Bacterial Genotoxin
Nature, 429, 2004
1VYB
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BU of 1vyb by Molmil
Endonuclease domain of human LINE1 ORF2p
分子名称: GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ...
著者Weichenrieder, O, Repanas, K, Perrakis, A.
登録日2004-04-25
公開日2004-06-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure, 12, 2004
1I9Y
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CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN
分子名称: PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
著者Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H.
登録日2001-03-21
公開日2001-05-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
1I9Z
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CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN IN COMPLEX WITH INOSITOL (1,4)-BISPHOSPHATE AND CALCIUM ION
分子名称: CALCIUM ION, D-MYO-INOSITOL-1,4-BISPHOSPHATE, PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
著者Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H.
登録日2001-03-21
公開日2001-05-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
1E9N
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A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism
分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
著者Beernink, P.T, Segelke, B.W, Rupp, B.
登録日2000-10-24
公開日2001-02-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1HD7
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A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism
分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
著者Beernink, P.T, Segelke, B.W, Rupp, B.
登録日2000-11-09
公開日2001-02-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1DE8
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HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA
分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*(3DR)P*GP*AP*TP*CP*G)-3'), MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE
著者Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A.
登録日1999-11-13
公開日2000-02-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature, 403, 2000
1DE9
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HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION
分子名称: 5'-d(*CP*TP*AP*C)-3', 5'-d(*GP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-d(P*(3DR)P*GP*AP*TP*C)-3', ...
著者Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A.
登録日1999-11-13
公開日2000-02-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
1DEW
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BU of 1dew by Molmil
CRYSTAL STRUCTURE OF HUMAN APE1 BOUND TO ABASIC DNA
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*(3DR)P*CP*GP*AP*CP*GP*AP*CP*G)-3', 5'-D(*GP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*C)-3', MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE, ...
著者Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A.
登録日1999-11-15
公開日2000-02-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
1BIX
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THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
分子名称: AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION
著者Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S.
登録日1998-06-19
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997

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