PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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4PLZ	Crystal structure of Plasmodium falciparum lactate dehydrogenase mutant W107fA. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase, OXAMIC ACID 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-20 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
1T2D	Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate 分子名称: GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. 登録日 2004-04-21 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
4PLG	Crystal structure of ancestral apicomplexan lactate dehydrogenase with oxamate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ... 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-16 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.192 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
4UUL	Apo trichomonas vaginalis lactate dehydrogenase L91R 分子名称: L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, L Theobald, D. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4H7P	Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin 分子名称: Malate dehydrogenase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-09-20 公開日 2012-10-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin To be Published
5HS4	Plasmdoium Vivax Lactate dehydrogenase 分子名称: L-lactate dehydrogenase 著者 Choi, S.J, Ban, C. 登録日 2016-01-25 公開日 2016-10-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.339 Å) 主引用文献 Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
4PLF	Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ... 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-16 公開日 2014-07-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
5NUE	Cytosolic Malate Dehydrogenase 1 (peroxide-treated) 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ETHOXYETHANOL, ... 著者 Young, D, Messens, J, Huang, J, Reichheld, J.-P. 登録日 2017-04-29 公開日 2018-02-28 最終更新日 2018-07-04 実験手法 X-RAY DIFFRACTION (1.35000277 Å) 主引用文献 Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
4UUM	Apo trichomonas vaginalis lactate dehydrogenase 分子名称: L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.368 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
3HHP	Malate dehydrogenase open conformation 分子名称: Malate dehydrogenase 著者 Zaitseva, J, Meneely, K.M, Lamb, A.L. 登録日 2009-05-15 公開日 2009-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution. Acta Crystallogr.,Sect.F, 65, 2009
4BGU	1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2013-03-28 公開日 2014-04-16 最終更新日 2019-03-06 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Insight Into Structural Evolution of Extremophilic Proteins To be Published
4TVO	Structure of Malate Dehydrogenase from Mycobacterium tuberculosis 分子名称: Malate dehydrogenase, SODIUM ION, SULFATE ION 著者 Ferraris, D.M, Rizzi, M. 登録日 2014-06-27 公開日 2015-01-14 最終更新日 2015-01-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis. Proteins, 83, 2015
4PLC	Crystal structure of ancestral apicomplexan lactate dehydrogenase with malate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ... 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-16 公開日 2014-07-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
2A94	Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH. 分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase 著者 Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. 登録日 2005-07-11 公開日 2006-01-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH. Biochemistry, 44, 2005
4I1I	Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin in complex with NAD 分子名称: 1,2-ETHANEDIOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-21 公開日 2012-12-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin in complex with NAD TO BE PUBLISHED
5UJK	Malate dehydrogenase from Methylobacterium extorquens, complexed with NAD 分子名称: CALCIUM ION, CHLORIDE ION, Malate dehydrogenase, ... 著者 Gonzalez, J.M. 登録日 2017-01-18 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase. Acta Crystallogr F Struct Biol Commun, 74, 2018
6KA1	E.coli Malate dehydrogenase 分子名称: Malate dehydrogenase 著者 Wang, H, Wang, M, Sun, H. 登録日 2019-06-19 公開日 2020-06-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.543 Å) 主引用文献 MDH is a major silver target in E. coli To Be Published
5W8J	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 分子名称: 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Lukacs, C.M, Moulin, A. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
7DBJ	Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase B chain, ... 著者 Sogabe, S, Miwa, M. 登録日 2020-10-20 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep, 11, 2021
3NEP	1.55A resolution structure of malate dehydrogenase from Salinibacter ruber 分子名称: Malate dehydrogenase 著者 Coquelle, N, Madern, D. 登録日 2010-06-09 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Gradual adaptive changes of a protein facing high salt concentrations. J.Mol.Biol., 404, 2010
5NQB	Rabbit Muscle L-lactate dehydrogenase in complex with malonate 分子名称: L-lactate dehydrogenase A chain, MALONATE ION 著者 Luisi, B.F, Olin-Sandoval, V. 登録日 2017-04-19 公開日 2017-05-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Nat Commun, 8, 2017
4M1Q	Crystal structure of L-lactate dehydrogenase from Bacillus selenitireducens MLS10, NYSGRC Target 029814. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, L-lactate dehydrogenase, PHOSPHATE ION 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-03 公開日 2013-08-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus selenitireducens MLS10, NYSGRC Target 029814. To be Published
5W8K	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 and NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ... 著者 Lukacs, C.M, Dranow, D.M. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
2X8L	Plasmodium falciparum lactate dehydrogenase apo structure 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE 著者 Birkinshaw, R.W, Brady, R.L. 登録日 2010-03-10 公開日 2010-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Apo Crystal Structure of Plasmodium Falciparum Lactate Dehydrogenase To be Published
4PLT	Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, malate dehydrogenase 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-19 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014

 

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