7DBJ
Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046
Summary for 7DBJ
Entry DOI | 10.2210/pdb7dbj/pdb |
Descriptor | L-lactate dehydrogenase B chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, ... (6 entities in total) |
Functional Keywords | lactate dehydrogenase, inhibitor, complex, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 150396.37 |
Authors | Sogabe, S.,Miwa, M. (deposition date: 2020-10-20, release date: 2021-10-20, Last modification date: 2023-11-29) |
Primary citation | Shibata, S.,Sogabe, S.,Miwa, M.,Fujimoto, T.,Takakura, N.,Naotsuka, A.,Kitamura, S.,Kawamoto, T.,Soga, T. Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep, 11:21353-21353, 2021 Cited by PubMed: 34725423DOI: 10.1038/s41598-021-00820-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.551 Å) |
Structure validation
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