7DBJ

Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	L-lactate dehydrogenase B chain	polymer	333	36548.2	4	UniProt (P07195) Pfam (PF00056) Pfam (PF02866)	Homo sapiens (Human)	LDH-B,LDH heart subunit,LDH-H,Renal carcinoma antigen NY-REN-46
2	E, H, L, Q (A, B, C, D)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	4	Chemie (NAI)
3	F, I, M, R (A, B, C, D)	OXAMIC ACID	non-polymer		89.0	4	Chemie (OXM)
4	G, J, N, O, S... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
5	K, P (C, D)	N-[[3-[2-[(phenylmethyl)amino]ethyl]-1H-indol-2-yl]methyl]cycloheptanamine	non-polymer		375.6	2	Chemie (H1U)
6	V, W, X, Y (A, B, C, D)	water	water		18.0	765	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	146192.8
Non-Polymers*	Number of molecules	17
	Total formula weight	4203.5
All*	Total formula weight	150396.4

*Water molecules are not included.