PDB: 194 件ウェブページステータス検索Chemie searchBIRD

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5NZQ	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-(1,3-oxazol-5-yl)aniline. 分子名称: 3-(1,3-oxazol-5-yl)aniline, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-05-14 公開日 2017-06-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
4NJO	crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in Entamoeba histolytica 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-3-phosphoglycerate dehydrogenase, putative, ... 著者 Singh, R.K, Gourinath, S. 登録日 2013-11-11 公開日 2014-10-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine. Febs J., 281, 2014
5OFV	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-fluoro-2-methylbenzoic acid 分子名称: 5-fluoranyl-2-methyl-benzoic acid, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-07-11 公開日 2017-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
4NU6	Crystal Structure of PTDH R301K 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase, SULFATE ION 著者 Nair, S.K, Chekan, J.R. 登録日 2013-12-03 公開日 2014-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
5NZP	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-Hydroxybenzisoxazole 分子名称: 1,2-benzoxazol-3-ol, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-05-14 公開日 2017-06-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
5OFM	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1H-indole 分子名称: 1-methylindol-5-amine, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-07-11 公開日 2017-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1H-indole To be published
5NZO	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 1-methyl-3-phenyl-1H-pyrazol-5-amine 分子名称: 2-methyl-5-phenyl-pyrazol-3-amine, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-05-14 公開日 2017-06-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
2Q50	Ensemble refinement of the protein crystal structure of a glyoxylate/hydroxypyruvate reductase from Homo sapiens 分子名称: Glyoxylate reductase/hydroxypyruvate reductase 著者 Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2007-05-31 公開日 2007-06-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
5OFW	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-Chloro-4-fluorobenzamide 分子名称: 3-chloranyl-4-fluoranyl-benzamide, D-3-phosphoglycerate dehydrogenase 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-07-11 公開日 2017-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
4XKJ	a Novel D-lactate Dehydrogenase from Sporolactobacillus sp 分子名称: D-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Bo, Y, Hui, D, Xiang, L. 登録日 2015-01-12 公開日 2015-08-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.148 Å) 主引用文献 a Novel D-lactate Dehydrogenase from Sporolactobacillus sp To Be Published
4XYG	GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) 分子名称: Formate dehydrogenase 著者 Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. 登録日 2015-02-02 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
4XYB	GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NADP(+) AND NaN3 分子名称: 1,2-ETHANEDIOL, AZIDE ION, Formate dehydrogenase, ... 著者 Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. 登録日 2015-02-02 公開日 2015-07-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
4XYE	GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NAD(+) 分子名称: Formate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. 登録日 2015-02-02 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
2W2K	Crystal structure of the apo forms of Rhodotorula graminis D- mandelate dehydrogenase at 1.8A. 分子名称: D-MANDELATE DEHYDROGENASE 著者 Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. 登録日 2008-11-02 公開日 2009-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
2W2L	Crystal structure of the holo forms of Rhodotorula graminis D- mandelate dehydrogenase at 2.5A. 分子名称: D-MANDELATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. 登録日 2008-11-02 公開日 2009-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
4S1V	Crystal structure of phosphoglycerate oxidoreductase from Vibrio Cholerae o395 分子名称: D-3-phosphoglycerate dehydrogenase-related protein 著者 Tarique, K.F, Rehman, S.A.A, Devi, S, Gourinath, S. 登録日 2015-01-15 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Phosphoglycerate Oxidoreductase from Vibrio Cholerae O395 To be Published
8GRV	Dictyostelium discoideum Lactate dehydrogenase (DicLDHA)with NAD 分子名称: ACETATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative D-lactate dehydrogenase 著者 Dao, O, Lee, K.H. 登録日 2022-09-02 公開日 2022-10-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dictyostelium discoideum Lactate dehydrogenase (DicLDHA) To Be Published
3DC2	Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis 分子名称: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID, SERINE 著者 Dey, S, Sacchettini, J.C. 登録日 2008-06-03 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase Biochemistry, 47, 2008
3DDN	Crystal structure of hydroxypyruvic acid phosphate bound D-3-phosphoglycerate dehydrogenase in mycobacterium tuberculosis 分子名称: 2-oxo-3-(phosphonooxy)propanoic acid, D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID 著者 Dey, S, Sacchettini, J.C. 登録日 2008-06-05 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase Biochemistry, 47, 2008
8HTY	Candida boidinii Formate Dehydrogenase Crystal Structure at 1.4 Angstrom Resolution 分子名称: Formate dehydrogenase, SULFATE ION 著者 Gul, M, Yuksel, B, Bulut, H, DeMirci, H. 登録日 2022-12-22 公開日 2023-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography. Acta Crystallogr D Struct Biol, 79, 2023
8I5Z	LDH Mutant P101Q-(An unexpected single-point mutation triggers the unleashing of catalytic potential of a NADH-dependent dehydrogenase) 分子名称: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein 著者 Liu, J.Q. 登録日 2023-01-26 公開日 2023-09-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Characterization of the Pro101Gln mutation that enhances the catalytic performance of T. indicus NADH-dependent d-lactate dehydrogenase. Structure, 31, 2023
8HPG	Crystal structure of phenylpyruvate reductase from Lactobacillus sp. CGMCC 9967 分子名称: Phenylpyruvate reductase 著者 Yang, J.H, Song, W. 登録日 2022-12-12 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.895 Å) 主引用文献 One-Pot Biocatalytic Transformation of L-DOPA to D-Danshensu To Be Published
8IQ7	Ambient Temperature Crystal Structure of Candida boidinii Formate Dehydrogenase 分子名称: Formate dehydrogenase 著者 Gul, M, DeMirci, H. 登録日 2023-03-16 公開日 2023-03-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography. Acta Crystallogr D Struct Biol, 79, 2023
8IVJ	Candida boidinii Formate Dehydrogenase V120T Mutant 分子名称: Formate dehydrogenase 著者 Gul, M, Yuksel, B, Bulut, H, DeMirci, H. 登録日 2023-03-28 公開日 2023-05-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography. Acta Crystallogr D Struct Biol, 79, 2023
8J3P	Formate dehydrogenase mutant from from Candida dubliniensis M4 complexed with NADP+ 分子名称: Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Ma, W, Zheng, Y.C, Geng, Q, Chen, C, Xu, J.H. 登録日 2023-04-17 公開日 2023-09-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Engineering a Formate Dehydrogenase for NADPH Regeneration. Chembiochem, 24, 2023

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