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1AFW
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BU of 1afw by Molmil
THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 3-KETOACETYL-COA THIOLASE
Authors:Mathieu, M, Wierenga, R.K.
Deposit date:1997-03-15
Release date:1997-06-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism.
J.Mol.Biol., 273, 1997
3GOA
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BU of 3goa by Molmil
Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase
Descriptor: 3-ketoacyl-CoA thiolase, CALCIUM ION, CHLORIDE ION, ...
Authors:Anderson, S.M, Skarina, T, Onopriyenko, O, Wawrzak, Z, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-03-18
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:

4W61
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BU of 4w61 by Molmil
Crystal structure of beta-ketoacyl thiolase B (BktB) from Ralstonia eutropha
Descriptor: Beta-ketothiolase BktB
Authors:Fage, C.D, Keatinge-Clay, A.T.
Deposit date:2014-08-19
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Coenzyme A-free activity, crystal structure, and rational engineering of a promiscuous beta-ketoacyl thiolase fromRalstonia eutropha.
J. Mol. Catal., B Enzym., 121, 2015
8ECM
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BU of 8ecm by Molmil
Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium
Descriptor: Acetyl-CoA acetyltransferase
Authors:Seo, H.S, Dhe-Paganon, S.
Deposit date:2022-09-02
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.
Nat Med, 29, 2023
7VTR
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BU of 7vtr by Molmil
3-ketoacyl-CoA thiolase Tfu_0875
Descriptor: Thiolase
Authors:Liu, L.X, Zhou, S.H, Deng, Y.
Deposit date:2021-10-30
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Rational Design of the Substrate Tunnel of beta-Ketothiolase Reveals a Local Cationic Domain Modulated Rule that Improves the Efficiency of Claisen Condensation
Acs Catalysis, 13, 2023
5ONC
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BU of 5onc by Molmil
Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch
Descriptor: CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase
Authors:Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C.
Deposit date:2017-08-03
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch.
ACS Infect Dis, 3, 2017
4O99
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BU of 4o99 by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4NZS
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BU of 4nzs by Molmil
Crystal structure of beta-ketothiolase BktB B from Ralstonia eutropha H16
Descriptor: Beta-ketothiolase BktB
Authors:Kim, E.J, Son, H, Kim, S, Kim, K.J.
Deposit date:2013-12-12
Release date:2014-11-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure and biochemical characterization of beta-keto thiolase B from polyhydroxyalkanoate-producing bacterium Ralstonia eutropha H16
Biochem.Biophys.Res.Commun., 444, 2014
4O9C
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BU of 4o9c by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, COENZYME A
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
5XYJ
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BU of 5xyj by Molmil
Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Zhou, P.F.
Deposit date:2017-07-08
Release date:2018-07-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
To Be Published
5F0V
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BU of 5f0v by Molmil
X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
Descriptor: 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase
Authors:Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N.
Deposit date:2015-11-28
Release date:2016-07-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
6L2G
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BU of 6l2g by Molmil
Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase
Descriptor: Acetyl-CoA-acetyltransferase, putative
Authors:Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W.
Deposit date:2019-10-03
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
6L2C
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BU of 6l2c by Molmil
Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA
Descriptor: Acetyl-CoA-acetyltransferase, putative, COENZYME A
Authors:Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W.
Deposit date:2019-10-03
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
5F38
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BU of 5f38 by Molmil
X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
Descriptor: 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase, COENZYME A, ...
Authors:Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N.
Deposit date:2015-12-02
Release date:2016-07-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
7PXP
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BU of 7pxp by Molmil
Benzoylsuccinyl-CoA thiolase
Descriptor: Benzoylsuccinyl-CoA thiolase subunit, ZINC ION
Authors:Ermler, U, Heider, H, Weidenweber, S, Demmer, U.
Deposit date:2021-10-08
Release date:2022-04-06
Last modified:2022-09-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
7PYT
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BU of 7pyt by Molmil
Benzoylsuccinyl-CoA thiolase with coenzyme A
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ...
Authors:Ermler, U, Heider, J, Weidenweber, S, Demmer, U.
Deposit date:2021-10-11
Release date:2022-04-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
5XZ5
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BU of 5xz5 by Molmil
Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
Descriptor: Acetyl-CoA acetyltransferase
Authors:Zhou, P.F, Zhu, Z.L.
Deposit date:2017-07-11
Release date:2018-07-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
To Be Published
4O9A
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BU of 4o9a by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
1QFL
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BU of 1qfl by Molmil
BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA IN COMPLEX WITH A REACTION INTERMEDIATE.
Descriptor: COENZYME A, PROTEIN (ACETOACETYL-COA THIOLASE), SULFATE ION
Authors:Modis, Y, Wierenga, R.K.
Deposit date:1999-04-12
Release date:2000-04-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism.
Structure Fold.Des., 7, 1999
3SVK
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BU of 3svk by Molmil
Crystal structure of Acetyl-CoA acetyltransferase from Mycobacterium avium
Descriptor: Acetyl-CoA acetyltransferase, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-07-12
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3SS6
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BU of 3ss6 by Molmil
Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase
Descriptor: Acetyl-CoA acetyltransferase, POTASSIUM ION, SULFATE ION
Authors:Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-07
Release date:2011-07-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase
TO BE PUBLISHED
1ULQ
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BU of 1ulq by Molmil
Crystal structure of tt0182 from Thermus thermophilus HB8
Descriptor: putative acetyl-CoA acetyltransferase
Authors:Ago, H, Hamada, K, Ida, K, Kanda, H, Sugahara, M, Yamamoto, M, Kuroishi, C, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-09-16
Release date:2004-11-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of tt0182 from Thermus thermophilus HB8
To be Published
7CW4
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BU of 7cw4 by Molmil
Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Hong, J, Kim, K.J.
Deposit date:2020-08-27
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579.
Biochem.Biophys.Res.Commun., 533, 2020
7XLY
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BU of 7xly by Molmil
Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis
Descriptor: Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION
Authors:Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K.
Deposit date:2022-04-23
Release date:2023-04-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties.
Febs J., 290, 2023
1DLU
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BU of 1dlu by Molmil
UNLIGANDED BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BIOSYNTHETIC THIOLASE, SULFATE ION
Authors:Modis, Y, Wierenga, R.K.
Deposit date:1999-12-12
Release date:2000-04-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase.
J.Mol.Biol., 297, 2000

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