1OX0
 
 | |
5MY0
 | | KS-MAT DI-DOMAIN OF MOUSE FAS WITH MALONYL-COA | | 分子名称: | COENZYME A, Fatty acid synthase, MALONYL-COENZYME A | | 著者 | Paithankar, K.S, Rittner, A, Huu, K.V, Grininger, M. | | 登録日 | 2017-01-25 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering.
ACS Chem. Biol., 13, 2018
|
|
5MY2
 | |
3E60
 | |
3G11
 | | Structure of E. coli FabF(C163Q) in complex with dihydrophenyl platensimycin | | 分子名称: | 3-({3-[(1S,4S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-4-phenyldecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2 | | 著者 | Soisson, S.M, Parthasarathy, G. | | 登録日 | 2009-01-29 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
3G0Y
 | | Structure of E. coli FabF(C163Q) in complex with dihydroplatensimycin | | 分子名称: | 3-({3-[(1S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxodecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2 | | 著者 | Soisson, S.M, Parthasarathy, G. | | 登録日 | 2009-01-29 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
1TQY
 | | The Actinorhodin Ketosynthase/Chain Length Factor | | 分子名称: | ACETYL GROUP, Actinorhodin polyketide putative beta-ketoacyl synthase 1, Actinorhodin polyketide putative beta-ketoacyl synthase 2, ... | | 著者 | Keatinge-Clay, A.T, Maltby, D.A, Medzihradszky, K.F, Khosla, C, Stroud, R.M. | | 登録日 | 2004-06-18 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An antibiotic factory caught in action.
Nat.Struct.Mol.Biol., 11, 2004
|
|
4XOX
 | | Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae | | 分子名称: | 3-oxoacyl-ACP synthase | | 著者 | Hou, J, Grabowski, M, Cymborowski, M, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-01-16 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae
to be published
|
|
2VZ8
 | |
2WGG
 | |
2WGD
 | | Crystal structure of KasA of Mycobacterium tuberculosis | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Luckner, S.R, Kisker, C. | | 登録日 | 2009-04-17 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
|
|
2WGE
 | |
7BC4
 | | Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris | | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | | 著者 | Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021
|
|
7BC5
 | | Cryo-EM structure of ACP domain from Pichia pastoris fatty acid synthase (FAS) | | 分子名称: | Fatty acid synthase subunit alpha | | 著者 | Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021
|
|
4Z37
 | |
7CPY
 | | Lovastatin nonaketide synthase with LovC | | 分子名称: | Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2020-08-08 | | 公開日 | 2021-01-13 | | 最終更新日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for the biosynthesis of lovastatin.
Nat Commun, 12, 2021
|
|
4ZDN
 | | Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS4 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION | | 著者 | Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-04-17 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-03-22 | | 実験手法 | X-RAY DIFFRACTION (2.509 Å) | | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
7CPX
 | | Lovastatin nonaketide synthase | | 分子名称: | Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2020-08-08 | | 公開日 | 2021-01-13 | | 最終更新日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural basis for the biosynthesis of lovastatin.
Nat Commun, 12, 2021
|
|
5W2P
 | | Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... | | 著者 | Capodagli, G.C, Neiditch, M.B. | | 登録日 | 2017-06-06 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
|
|
5W2Q
 | | Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... | | 著者 | Capodagli, G.C, Neiditch, M.B. | | 登録日 | 2017-06-06 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
|
|
5W2O
 | | Crystal structure of Mycobacterium tuberculosis KasA | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, CHLORIDE ION, ... | | 著者 | Capodagli, G.C, Neiditch, M.B. | | 登録日 | 2017-06-06 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
|
|
5W2S
 | |
5BP1
 | |
6U5T
 | |
8EE0
 | | KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment 1B2 | | 分子名称: | 1B2 antibody heavy chain, 1B2 antibody light chain, 6-deoxyerythronolide B synthase | | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | | 登録日 | 2022-09-06 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
|
|
