PDB: 125 件ウェブページステータス検索Chemie searchBIRD

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6DJK	Structure of DNA polymerase III subunit beta from Rickettsia typhi in complex with a natural product 分子名称: 1,2-ETHANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-05-25 公開日 2019-05-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of DNA polymerase III subunit beta from Rickettsia typhi in complex with a natural product to be published
4K3Q	E. coli sliding clamp in complex with AcQLDAF 分子名称: (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-11 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3M	E.coli sliding clamp in complex with AcALDLF peptide 分子名称: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-11 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
6PTV	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-07-16 公開日 2019-08-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin To Be Published
4K3K	E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid 分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-10 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4MJP	E. coli sliding clamp in complex with (R)-Vedaprofen 分子名称: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-09-04 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.855 Å) 主引用文献 DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
4K3R	E. coli sliding clamp in complex with AcQLDLA 分子名称: (ACE)QLDLA, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-11 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
7AZ5	DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound 分子名称: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ... 著者 Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. 登録日 2020-11-16 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
5WCE	Caulobacter crescentus pol III beta 分子名称: DNA polymerase III subunit beta 著者 Oakley, A.J. 登録日 2017-06-30 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Pol III beta from Caulobacter crescentus To Be Published
3QSB	Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile 分子名称: (1R,5R)-5-{(1Z)-N-[(4'-fluorobiphenyl-4-yl)methoxy]butanimidoyl}-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile, DNA polymerase III subunit beta 著者 Wijffels, G, Johnson, W.M, Oakley, A.J, Turner, K, Epa, V.C, Briscoe, S.J, Polley, M, Liepa, A.J, Hofmann, A, Buchardt, J, Christensen, C, Prosselkov, P, Dalrymple, B.P, Alewood, P.F, Jennings, P.A, Dixon, N.E, Winkler, D.A. 登録日 2011-02-20 公開日 2011-06-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Binding inhibitors of the bacterial sliding clamp by design J.Med.Chem., 54, 2011
4N9A	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid 分子名称: (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
1UNN	Complex of beta-clamp processivity factor and little finger domain of PolIV 分子名称: DNA POLYMERASE III BETA SUBUNIT, DNA POLYMERASE IV, SULFATE ION 著者 Bunting, K.A, Roe, S.M, Pearl, L.H. 登録日 2003-09-11 公開日 2003-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Recruitment of Translesion DNA Polymerase Pol Iv/Dinb to the Beta-Clamp Embo J., 22, 2003
3D1E	Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide 分子名称: DNA polymerase III subunit beta, decamer from polymerase II C-terminal 著者 Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. 登録日 2008-05-05 公開日 2008-07-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa, 105, 2008
2XUR	The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication 分子名称: DNA POLYMERASE III SUBUNIT BETA 著者 Johnsen, L, Morigen, Dalhus, B, Bjoras, M, Flaatten, I, Waldminghaus, T, Skarstad, K. 登録日 2010-10-20 公開日 2011-02-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The G157C Mutation in the Escherichia Coli Sliding Clamp Specifically Affects Initiation of Replication. Mol.Microbiol., 79, 2011
3BEP	Structure of a sliding clamp on DNA 分子名称: 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ... 著者 Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M. 登録日 2007-11-19 公開日 2008-01-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure of a sliding clamp on DNA Cell(Cambridge,Mass.), 132, 2008
5AGV	The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. 分子名称: (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ... 著者 Lukat, P, Kling, A, Heinz, D.W, Mueller, R. 登録日 2015-02-03 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
7AZ6	DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound 分子名称: ACETATE ION, Beta sliding clamp, CHLORIDE ION, ... 著者 Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. 登録日 2020-11-16 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZF	DNA polymerase sliding clamp from Escherichia coli with peptide 8 bound 分子名称: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. 登録日 2020-11-16 公開日 2021-12-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
6IZO	Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus 分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER 著者 Jiang, X, Zhang, L, Teng, M, Li, X. 登録日 2018-12-20 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication. Febs J., 287, 2020
4S3I	Crystal structure of beta clamp from Helicobacter pylori 分子名称: DNA polymerase III subunit beta 著者 Pandey, P, Tarique, K.F, Abdul Rehman, S.A, Gourinath, S. 登録日 2015-01-28 公開日 2016-02-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.946 Å) 主引用文献 Structural insight into beta-Clamp and its interaction with DNA Ligase in Helicobacter pylori. Sci Rep, 6, 2016
3Q4L	Structure of a small peptide ligand bound to E.coli DNA sliding clamp 分子名称: DNA polymerase III subunit beta, SODIUM ION, peptide ligand 著者 Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. 登録日 2010-12-23 公開日 2011-12-28 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011
6JIR	Crystal structure of C. crescentus beta sliding clamp with PEG bound to putative beta-motif tethering region 分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER, ... 著者 Jiang, X, Teng, M, Li, X. 登録日 2019-02-23 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication. Febs J., 287, 2020
5FXT	Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen 分子名称: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, DNA POLYMERASE III SUBUNIT BETA 著者 Pandey, P, Gourinath, S. 登録日 2016-03-02 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
4N97	E. coli sliding clamp in complex with 5-nitroindole 分子名称: 5-nitro-1H-indole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
6FVL	DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide 分子名称: Beta sliding clamp, GLYCEROL, P7 peptide, ... 著者 Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. 登録日 2018-03-04 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019

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