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5FRQ
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Crystal Structure of Helicobacter pylori beta clamp bound to DNA ligase peptide
Descriptor: DNA LIGASE, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2015-12-21
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insight Into Beta-Clamp and its Interaction with DNA Ligase in Helicobacter Pylori
Sci.Rep., 6, 2016
5FKW
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BU of 5fkw by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon)
Descriptor: DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FXT
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BU of 5fxt by Molmil
Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen
Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-03-02
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
5FKV
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BU of 5fkv by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex)
Descriptor: DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.04 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FVE
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BU of 5fve by Molmil
Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide
Descriptor: 3,4-difluorobenzamide, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-02-05
Release date:2017-02-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
5G4Q
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BU of 5g4q by Molmil
H.pylori Beta clamp in complex with 5-chloroisatin
Descriptor: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-05-16
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
5G48
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BU of 5g48 by Molmil
H.pylori Beta clamp in complex with Diflunisal
Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-05-06
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal.
FEBS Lett., 591, 2017
4K3Q
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E. coli sliding clamp in complex with AcQLDAF
Descriptor: (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K74
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BU of 4k74 by Molmil
The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor.
Descriptor: DNA polymerase III subunit beta, UmuC peptide
Authors:Patoli, A.A, Winter, J.A, Bunting, K.A.
Deposit date:2013-04-16
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor.
Bmc Struct.Biol., 13, 2013
4K3M
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BU of 4k3m by Molmil
E.coli sliding clamp in complex with AcALDLF peptide
Descriptor: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3O
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BU of 4k3o by Molmil
E. coli sliding clamp in complex with AcQADLF
Descriptor: (ACE)QADLF, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3K
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BU of 4k3k by Molmil
E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid
Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-10
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3P
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BU of 4k3p by Molmil
E. coli sliding clamp in complex with AcQLALF
Descriptor: (ACE)QLALF, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3R
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BU of 4k3r by Molmil
E. coli sliding clamp in complex with AcQLDLA
Descriptor: (ACE)QLDLA, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3L
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BU of 4k3l by Molmil
E. coli sliding clamp in complex with AcLF dipeptide
Descriptor: 1,2-ETHANEDIOL, ACETYL GROUP, CALCIUM ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-10
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3S
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BU of 4k3s by Molmil
E. coli sliding clamp in P1 crystal space group
Descriptor: CALCIUM ION, DNA polymerase III subunit beta, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4MJR
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BU of 4mjr by Molmil
E. coli sliding clamp in complex with (S)-Carprofen
Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJP
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BU of 4mjp by Molmil
E. coli sliding clamp in complex with (R)-Vedaprofen
Descriptor: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJQ
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BU of 4mjq by Molmil
E. coli sliding clamp in complex with Bromfenac
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4N96
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BU of 4n96 by Molmil
E. coli sliding clamp in complex with 6-nitroindazole
Descriptor: 6-NITROINDAZOLE, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N95
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BU of 4n95 by Molmil
E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione
Descriptor: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N94
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BU of 4n94 by Molmil
E. coli sliding clamp in complex with 3,4-difluorobenzamide
Descriptor: 1,2-ETHANEDIOL, 3,4-difluorobenzamide, CALCIUM ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N98
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BU of 4n98 by Molmil
E. coli sliding clamp in complex with 4'-fluorobiphenyl-4-carboxylic acid
Descriptor: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N9A
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BU of 4n9a by Molmil
E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid
Descriptor: (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N97
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E. coli sliding clamp in complex with 5-nitroindole
Descriptor: 5-nitro-1H-indole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014

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