PDB: 40 resultsInfo pagesStatus searchChemie searchBIRD

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6FGS	Solution structure of p300Taz2-p73TA1 Descriptor: Histone acetyltransferase p300,Tumor protein p73, ZINC ION Authors: Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. Deposit date: 2018-01-11 Release date: 2018-05-30 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
6FGN	Solution Structure of p300Taz2-p63TA Descriptor: Histone acetyltransferase p300,Tumor protein 63, ZINC ION Authors: Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. Deposit date: 2018-01-11 Release date: 2018-05-30 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
7LVS	The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION Authors: Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E. Deposit date: 2021-02-26 Release date: 2021-07-28 Last modified: 2021-12-15 Method: X-RAY DIFFRACTION (2.02 Å) Cite: The molecular basis of allostery in a facilitated dissociation process. Structure, 29, 2021
7QGS	Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid) Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION Authors: Hegedus, Z, Wilson, A.J, Edwards, T.A. Deposit date: 2021-12-10 Release date: 2022-05-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Understanding p300-transcription factor interactions using sequence variation and hybridization. Rsc Chem Biol, 3, 2022
7XEZ	NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2 Descriptor: Histone acetyltransferase p300,NUT family member 1, ZINC ION Authors: Yu, D, Zeng, L, Zhou, M.-M. Deposit date: 2022-03-31 Release date: 2023-04-12 Method: SOLUTION NMR Cite: Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation To Be Published
7XFG	NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1 Descriptor: Histone acetyltransferase p300, NUT family member 1, ZINC ION Authors: Yu, D, Zeng, L, Zhou, M.-M. Deposit date: 2022-04-01 Release date: 2023-04-12 Method: SOLUTION NMR Cite: Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation To Be Published
8E1D	NMR-derived ensemble of the TAZ2 domain of p300 bound to the microphthalmia-associated transcription factor Descriptor: Histone acetyltransferase p300, Microphthalmia-associated transcription factor, ZINC ION Authors: Langelaan, D.N, Branch, M. Deposit date: 2022-08-10 Release date: 2023-06-21 Last modified: 2023-07-12 Method: SOLUTION NMR Cite: Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor. Biochim Biophys Acta Mol Cell Res, 1870, 2023
8HAL	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAG	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution) Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAH	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution) Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAI	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution) Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAJ	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution) Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAM	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAK	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 4 (4.5 angstrom resolution) Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAN	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3 Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023

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