5VVL
 
 | | Cas1-Cas2 bound to full-site mimic with Ni | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (11-MER), ... | | 著者 | Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A. | | 登録日 | 2017-05-19 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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5VVK
 | | Cas1-Cas2 bound to full-site mimic | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*CP*CP*AP*CP*CP*AP*GP*TP*G)-3'), ... | | 著者 | Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A. | | 登録日 | 2017-05-19 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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5VVJ
 | | Cas1-Cas2 bound to half-site intermediate | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (112-MER), ... | | 著者 | Wright, A.V, Knott, G.J, Doxzen, K.W, Doudna, J.A. | | 登録日 | 2017-05-19 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | | 主引用文献 | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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7MID
 | | Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA | | 分子名称: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ... | | 著者 | Hu, C.Y, Ke, A.K. | | 登録日 | 2021-04-16 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI9
 | | Full integration complex of Cas1/Cas2 from Cas4-containing system | | 分子名称: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ... | | 著者 | Hu, C.Y, Ke, A.K. | | 登録日 | 2021-04-16 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI4
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7MI5
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7MIB
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5DS4
 | | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER) | | 著者 | Nunez, J.K, Harrington, L.B, Kranzusch, P.J, Engelman, A.N, Doudna, J.A. | | 登録日 | 2015-09-16 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
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5DS6
 | | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA with splayed ends | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | 著者 | Nunez, J.K, Harrington, L.B, Kranzusch, P.J, Engelman, A.N, Doudna, J.A. | | 登録日 | 2015-09-16 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.352 Å) | | 主引用文献 | Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
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5DQU
 | | Crystal Structure of Cas-DNA-10 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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5DS5
 | | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA and Mg | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | 著者 | Nunez, J.K, Harrington, L.B, Kranzusch, P.J, Engelman, A.N, Doudna, J.A. | | 登録日 | 2015-09-16 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | | 主引用文献 | Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
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5DQZ
 | | Crystal Structure of Cas-DNA-PAM complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (36-MER), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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5DQT
 | | Crystal Structure of Cas-DNA-22 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (33-MER), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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5DLJ
 | | Crystal Structure of Cas-DNA-N1 complex | | 分子名称: | 39-mer DNA N1-F, 39-mer DNA N1-R, CRISPR-associated endonuclease Cas1, ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-05 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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8FLJ
 | | Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA | | 分子名称: | CRISPR leader and repeat, anti-sense strand of DNA, CRISPR leader, ... | | 著者 | Santiago-Frangos, A, Henriques, W.S, Wiegand, T, Gauvin, C, Buyukyoruk, M, Neselu, K, Eng, E.T, Lander, G.C, Wiedenheft, B. | | 登録日 | 2022-12-21 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays.
Nat.Struct.Mol.Biol., 30, 2023
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7KFU
 | | Cas6-RT-Cas1--Cas2 complex | | 分子名称: | Cas2, Cas6-RT-Cas1 | | 著者 | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | 登録日 | 2020-10-14 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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7KFT
 | | Partial Cas6-RT-Cas1--Cas2 complex | | 分子名称: | Cas2, Cas6-RT-Cas1 | | 著者 | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | 登録日 | 2020-10-14 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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5WFE
 | | Cas1-Cas2-IHF-DNA holo-complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | 著者 | Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A. | | 登録日 | 2017-07-11 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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