3B7U
| Leukotriene A4 Hydrolase Complexed with KELatorphan | Descriptor: | ACETIC ACID, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | Authors: | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | Deposit date: | 2007-10-31 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B7R
| Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 | Descriptor: | IMIDAZOLE, Leukotriene A-4 hydrolase, N-[3-[(1-AMINOETHYL)(HYDROXY)PHOSPHORYL]-2-(1,1'-BIPHENYL-4-YLMETHYL)PROPANOYL]ALANINE, ... | Authors: | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | Deposit date: | 2007-10-31 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.811 Å) | Cite: | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B7T
| [E296Q]LTA4H in complex with Arg-Ala-Arg substrate | Descriptor: | IMIDAZOLE, Leukotriene A-4 hydrolase, RAR peptide, ... | Authors: | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | Deposit date: | 2007-10-31 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3EBG
| Structure of the M1 Alanylaminopeptidase from malaria | Descriptor: | GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2008-08-27 | Release date: | 2009-01-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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3EBH
| Structure of the M1 Alanylaminopeptidase from malaria complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, GLYCEROL, M1 family aminopeptidase, ... | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2008-08-27 | Release date: | 2009-01-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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3EBI
| Structure of the M1 Alanylaminopeptidase from malaria complexed with the phosphinate dipeptide analog | Descriptor: | (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, GLYCEROL, M1 family aminopeptidase, ... | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2008-08-27 | Release date: | 2009-01-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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3FTY
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3FUF
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3FU3
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3FUK
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3FU0
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3FTX
| Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol, ACETATE ION, ... | Authors: | Davies, D.R. | Deposit date: | 2009-01-13 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
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3FUH
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3FUI
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3FTU
| Leukotriene A4 hydrolase in complex with dihydroresveratrol | Descriptor: | 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol, ACETATE ION, IMIDAZOLE, ... | Authors: | Davies, D.R. | Deposit date: | 2009-01-13 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
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3FU6
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3FUN
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3FTS
| Leukotriene A4 hydrolase in complex with resveratrol | Descriptor: | ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | Authors: | Davies, D.R. | Deposit date: | 2009-01-13 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
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3FTW
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3FUD
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3FUE
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3FU5
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3FUJ
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3FTV
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3FUM
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