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4JRR	Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila Descriptor: GLYCEROL, SULFATE ION, Thiol:disulfide interchange protein DsbA Authors: Shumilin, I.A, Jameson-Lee, M, Cymborowski, M, Domagalski, M.J, Chertihin, O, Kpadeh, Z.Z, Yeh, A.J, Hoffman, P.S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2013-03-21 Release date: 2013-04-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila To be Published
3C7M	Crystal structure of reduced DsbL Descriptor: CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G. Deposit date: 2008-02-07 Release date: 2008-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.55 Å) Cite: DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli. J.Mol.Biol., 380, 2008
3L9U	Crystal Structure of Salmonella enterica serovar Typhimurium DsbL Descriptor: Disulfide isomerase Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.568 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
4OCE	Crystal structure of the disulfide oxidoreductase DsbA from Proteus mirabilis Descriptor: MALONATE ION, Thiol:disulfide interchange protein Authors: Kurth, F, Martin, J.L. Deposit date: 2014-01-09 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.768 Å) Cite: Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
3L9V	Crystal Structure of Salmonella enterica serovar Typhimurium SrgA Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
4K2D	Crystal structure of Burkholderia Pseudomallei DsbA Descriptor: GLYCEROL, Thiol:disulfide interchange protein Authors: McMahon, R.M. Deposit date: 2013-04-09 Release date: 2013-08-14 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo. Antioxid Redox Signal, 20, 2014
5XWH	Structure of FrnE, a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in the presence of GSH Descriptor: FrnE protein Authors: Bihani, S.C, Panicker, L, Kumar, V. Deposit date: 2017-06-29 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of FrnE, a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in the presence of GSH To Be Published
4MCU	Crystal structure of disulfide oxidoreductase from Klebsiella pneumoniae in reduced state Descriptor: Thiol:disulfide interchange protein Authors: Kurth, F, Premkumar, L, Martin, J.L. Deposit date: 2013-08-21 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes. Plos One, 8, 2013
5XUR	Crystal Structure of Rv2466c C22S Mutant Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Thioredoxin-like reductase Rv2466c Authors: Zhang, X, Li, H. Deposit date: 2017-06-25 Release date: 2018-03-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.996 Å) Cite: Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis, 4, 2018
3L9S	Crystal Structure of Salmonella enterica serovar Typhimurium DsbA Descriptor: Thiol:disulfide interchange protein Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
1DSB	CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO Descriptor: DSBA Authors: Martin, J.L, Bardwell, J.C.A, Kuriyan, J. Deposit date: 1993-05-24 Release date: 1994-01-31 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365, 1993
3DKS	DsbA substrate complex Descriptor: Thiol:disulfide interchange protein dsbA, siga peptide Authors: Paxman, J.J, Borg, N.A, Horne, J, Rossjohn, J, Thompson, P.E, Piek, S, Kahler, C.M, Sakellaris, H, Scanlon, M.J. Deposit date: 2008-06-25 Release date: 2009-05-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes J.Biol.Chem., 284, 2009
4OD7	Complex structure of Proteus mirablis DsbA (C30S) with a non-covalently bound peptide PWATCDS Descriptor: (ACE)PWATCDS(NH2) Peptide, THIOCYANATE ION, Thiol:disulfide interchange protein Authors: Kurth, F, Premkumar, L, Martin, J.L. Deposit date: 2014-01-10 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.597 Å) Cite: Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
4TKY	The complex structure of E. coli DsbA bound to a peptide at the DsbA/DsbB interface Descriptor: ACETYL GROUP, AMINO GROUP, PRO-PHE-ALA-THR-CYS-ASP-SER, ... Authors: Premkumar, L, Martin, J.L. Deposit date: 2014-05-28 Release date: 2015-01-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence. J.Med.Chem., 58, 2015
5VYO	The complex structure of Burkholderia pseudomallei DsbA bound to a peptide Descriptor: Disulfide bond formation protein B, Thiol:disulfide interchange protein Authors: McMahon, R.M, Martin, J.L. Deposit date: 2017-05-25 Release date: 2018-03-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB. Infect. Immun., 86, 2018
3FZ5	Crystal structure of possible 2-hydroxychromene-2-carboxylate isomerase from Rhodobacter sphaeroides Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLUTATHIONE, ... Authors: Chang, C, Hatzos, C, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2009-01-23 Release date: 2009-02-03 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of possible 2-hydroxychromene-2-carboxylate isomerase from Rhodobacter sphaeroides To be Published
1FVJ	THE 2.06 ANGSTROM STRUCTURE OF THE H32Y MUTANT OF THE DISULFIDE BOND FORMATION PROTEIN (DSBA) Descriptor: DISULFIDE BOND FORMATION PROTEIN Authors: Martin, J.L, Guddat, L.W. Deposit date: 1996-08-28 Release date: 1997-05-15 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
1FVK	THE 1.7 ANGSTROM STRUCTURE OF WILD TYPE DISULFIDE BOND FORMATION PROTEIN (DSBA) Descriptor: DISULFIDE BOND FORMATION PROTEIN Authors: Martin, J.L, Guddat, L.W. Deposit date: 1996-08-28 Release date: 1997-08-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
4NXI	Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein Authors: Albesa-Jove, D, Urresti, S, Comino, N, Guerin, M.E. Deposit date: 2013-12-09 Release date: 2014-10-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
3H93	Crystal Structure of Pseudomonas aeruginosa DsbA Descriptor: GLYCEROL, Thiol:disulfide interchange protein dsbA Authors: Shouldice, S.R. Deposit date: 2009-04-29 Release date: 2009-12-08 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.501 Å) Cite: Characterization of the DsbA Oxidative Folding Catalyst from Pseudomonas aeruginosa Reveals a Highly Oxidizing Protein that Binds Small Molecules. Antioxid Redox Signal, 12, 2010
2MBT	NMR study of PaDsbA Descriptor: Thiol:disulfide interchange protein DsbA Authors: Rimmer, K, Mohanty, B, Scanlon, M.J. Deposit date: 2013-08-03 Release date: 2014-11-12 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
6XSP	Crystal structure of E.coli DsbA in complex with 2-(2,6-bis(3-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [2,6-bis(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-15 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XSQ	Crystal structure of E.coli DsbA in complex with 2-(6-(3-methoxyphenyl)-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-16 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XT3	Crystal structure of E.coli DsbA in complex with 3-(3-(carboxymethyl)-6-(3-methoxyphenyl)benzofuran-2-yl)benzoic acid Descriptor: 3-[3-(carboxymethyl)-6-(3-methoxyphenyl)-1-benzofuran-2-yl]benzoic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2020-07-17 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
1R4W	Crystal structure of Mitochondrial class kappa glutathione transferase Descriptor: GLUTATHIONE, Glutathione S-transferase, mitochondrial Authors: Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N. Deposit date: 2003-10-08 Release date: 2004-02-03 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1 Biochemistry, 43, 2004

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