4NXI
Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis
Summary for 4NXI
Entry DOI | 10.2210/pdb4nxi/pdb |
Descriptor | Uncharacterized protein, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | thioredoxin, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 46647.68 |
Authors | Albesa-Jove, D.,Urresti, S.,Comino, N.,Guerin, M.E. (deposition date: 2013-12-09, release date: 2014-10-22, Last modification date: 2023-11-08) |
Primary citation | Albesa-Jove, D.,Chiarelli, L.R.,Makarov, V.,Pasca, M.R.,Urresti, S.,Mori, G.,Salina, E.,Vocat, A.,Comino, N.,Mohorko, E.,Ryabova, S.,Pfieiffer, B.,Lopes Ribeiro, A.L.,Rodrigo-Unzueta, A.,Tersa, M.,Zanoni, G.,Buroni, S.,Altmann, K.H.,Hartkoorn, R.C.,Glockshuber, R.,Cole, S.T.,Riccardi, G.,Guerin, M.E. Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. Acs Chem.Biol., 9:1567-1575, 2014 Cited by PubMed: 24877756DOI: 10.1021/cb500149m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.698 Å) |
Structure validation
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