PDB: 149 件ウェブページステータス検索Chemie searchBIRD

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2GDG	Crystal structure of covalently modified macrophage inhibitory factor 分子名称: Macrophage migration inhibitory factor 著者 Golubkov, P.A, Hackert, M.L. 登録日 2006-03-16 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate. Bioorg.Chem., 34, 2006
5V73	Crystal structure of N110A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2017-03-17 公開日 2018-03-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of N110A mutant of human macrophage migration inhibitory factor To Be Published
6CUQ	Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica 分子名称: 1,2-ETHANEDIOL, Macrophage migration inhibitory factor-like protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-03-26 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica to be published
4NWR	Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T33-28 分子名称: Macrophage migration inhibitory factor-like protein, integron gene cassette protein 著者 McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. 登録日 2013-12-06 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
3CE4	Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Crichlow, G.V, Lolis, E. 登録日 2008-02-28 公開日 2008-12-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48, 2009
5XEJ	Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX 分子名称: (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, Macrophage migration inhibitory factor, SULFATE ION 著者 Takimoto-Kamimura, M, Fukushima, K. 登録日 2017-04-05 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of macrophage migration inhibitory factor in complex with methotrexate. Acta Crystallogr D Struct Biol, 77, 2021
8AP3	Structure of A. thaliana MIF/D-DT-like protein-2 (MDL2) 分子名称: MIF homologue 著者 Manjula, R, Basquin, J, Lolis, E. 登録日 2022-08-09 公開日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of A. thaliana MIF/D-DT-like protein-2 (MDL2) To Be Published
3L5T	Crystal structure of macrophage migration inhibitory factor (MIF) with thiophenepiperazinylquinolinone inhibitor at 1.86A resolution 分子名称: 1-methyl-2-oxo-4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]-1,2-dihydroquinoline-3-carbonitrile, Macrophage migration inhibitory factor, SULFATE ION 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
6ICE	Crystal structure of Hamster MIF 分子名称: Macrophage migration inhibitory factor 著者 Sundaram, R, Vasudevan, D. 登録日 2018-09-05 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer. Sci Rep, 9, 2019
7KQX	MIF Y99C homotrimeric mutant 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Manjula, R, Georgios, P, Lolis, E.J. 登録日 2020-11-18 公開日 2022-01-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies. Front Mol Biosci, 9, 2022
2WKF	Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum 分子名称: GLYCEROL, MACROPHAGE MIGRATION INHIBITORY FACTOR 著者 Dobson, S.E, Augustijn, K.D, Brannigan, J.A, Dodson, E.J, Waters, A.P, Wilkinson, A.J. 登録日 2009-06-11 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei. Protein Sci., 18, 2009
5EIZ	Crystal structure of Y99A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-10-30 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 2018
8UR2	Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I41 form) 分子名称: IODIDE ION, MACROPHAGE MIGRATION INHIBITORY FACTOR, PYRUVIC ACID 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-10-25 公開日 2023-11-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I41 form) To be published
8IMR	Structure of ligand-free human macrophage migration inhibitory factor 分子名称: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H. 登録日 2023-03-07 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis To Be Published
4DH4	Macrophage migration inhibitory factor Toxoplasma gondii 分子名称: MIF, SULFATE ION 著者 Richardson, J.M. 登録日 2012-01-27 公開日 2012-11-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Biochemical and Immunological Characterization of Toxoplasma gondii Macrophage Migration Inhibitory Factor. J.Biol.Chem., 288, 2013
4K9G	1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound 分子名称: (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one, 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one, CHLORIDE ION, ... 著者 Crichlow, G.V, Al-Abed, Y, Lolis, E.J. 登録日 2013-04-19 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models. INT J ONCOL., 45, 2014
1UIZ	Crystal Structure Of Macrophage Migration Inhibitory Factor From Xenopus Laevis. 分子名称: Macrophage Migration Inhibitory Factor 著者 Suzuki, M, Takamura, Y, Maeno, M, Tochinai, S, Iyaguchi, D, Tanaka, I, Nishihira, J, Ishibashi, T. 登録日 2003-07-24 公開日 2004-05-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Xenopus laevis Macrophage Migration Inhibitory Factor Is Essential for Axis Formation and Neural Development. J.Biol.Chem., 279, 2004
8DQA	Structure of A. thaliana MIF/D-DT-like protein-3 (MDL3) 分子名称: LS1-like protein 著者 Manjula, R, Basquin, J, Lolis, E. 登録日 2022-07-18 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of A. thaliana MIF/D-DT-like protein-3 (MDL3) To Be Published
3T5S	Structure of macrophage migration inhibitory factor from Giardia lamblia 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-07-28 公開日 2011-08-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. J.Struct.Funct.Genom., 14, 2013
8DQ6	Structure of A. thaliana MIF/D-DT-like protein-1 (MDL1) 分子名称: CALCIUM ION, MIF/D-DT-like protein-1 著者 Manjula, R, Basquin, J, Lolis, E. 登録日 2022-07-18 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structure of A. thaliana MIF/D-DT-like protein-1 (AtMDL1) To Be Published
7XTX	High resolution crystal structure of human macrophage migration inhibitory factor in complex with methotrexate 分子名称: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H. 登録日 2022-05-18 公開日 2023-05-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis To Be Published
7XVX	Neutron crystal structure of human macrophage migration inhibitory factor 分子名称: Macrophage migration inhibitory factor 著者 Ezawa, T, Tamada, T, Odaka, M, Matsumura, H. 登録日 2022-05-25 公開日 2023-05-31 最終更新日 2024-04-03 実験手法 NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION 主引用文献 Neutron crystal structure of human macrophage migration inhibitory factor To Be Published
3U18	Chicago Sky Blue 6B, A Novel Inhibitor for Macrophage Migration Inhibitory Factor 分子名称: 1,2-ETHANEDIOL, 6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid), GLYCEROL, ... 著者 Asojo, O.A. 登録日 2011-09-29 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF). J.Biol.Chem., 287, 2012
1HFO	The Structure of the Macrophage Migration Inhibitory Factor from Trichinella Spiralis. 分子名称: MIGRATION INHIBITORY FACTOR 著者 Roe, S.M, Meyer, D.J. 登録日 2000-12-07 公開日 2001-08-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Macrophage Migration Inhibitory Factor of the Parasitic Nematode Trichinella Spiralis Biochem.J., 357, 2001
8CA0	Macrophage inhibitory factor (MIF) in complex with small molecule PAV174 分子名称: 1-ethyl-9-methyl-3,7-dipyrrolidin-1-yl-phenothiazine, Macrophage migration inhibitory factor 著者 Mueller, A, Torres, F, Roland, R, Korth, C. 登録日 2023-01-24 公開日 2024-02-07 実験手法 SOLUTION NMR 主引用文献 Oxidized MIF is a drug target at the molecular intersection between immune activation and tau cellular pathology To Be Published

 

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