6Q70
 
 | | Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of HEPES | | Descriptor: | Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | | Deposit date: | 2018-12-12 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
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6Q71
 | | Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of Bis-Tris propane | | Descriptor: | Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | | Deposit date: | 2018-12-12 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
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6Q72
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2RJG
 | | Crystal structure of biosynthetic alaine racemase from Escherichia coli | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | Authors: | Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. | | Deposit date: | 2007-10-15 | | Release date: | 2008-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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2RJH
 | | Crystal structure of biosynthetic alaine racemase in D-cycloserine-bound form from Escherichia coli | | Descriptor: | Alanine racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, SULFATE ION | | Authors: | Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. | | Deposit date: | 2007-10-15 | | Release date: | 2008-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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2SFP
 | | ALANINE RACEMASE WITH BOUND PROPIONATE INHIBITOR | | Descriptor: | PROPANOIC ACID, PROTEIN (ALANINE RACEMASE), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Morollo, A.A, Petsko, G.A, Ringe, D. | | Deposit date: | 1999-02-16 | | Release date: | 1999-02-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
Biochemistry, 38, 1999
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6SCZ
 | | Mycobacterium tuberculosis alanine racemase inhibited by DCS | | Descriptor: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | de Chiara, C, Purkiss, A, Prosser, G, Homsak, M, de Carvalho, L.P.S. | | Deposit date: | 2019-07-26 | | Release date: | 2020-04-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition.
Nat.Chem.Biol., 16, 2020
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2VD8
 | | The crystal structure of alanine racemase from Bacillus anthracis (BA0252) | | Descriptor: | ALANINE RACEMASE, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Au, K, Ren, J, Walter, T.S, Harlos, K, Nettleship, J.E, Owens, R.J, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | Deposit date: | 2007-10-01 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
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2VD9
 | | The crystal structure of alanine racemase from Bacillus anthracis (BA0252) with bound L-Ala-P | | Descriptor: | (1S)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]ETHYLPHOSPHONIC ACID, ALANINE RACEMASE, CHLORIDE ION, ... | | Authors: | Au, K, Ren, J, Walter, T.S, Harlos, K, Nettleship, J.E, Owens, R.J, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | Deposit date: | 2007-10-01 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
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4LUS
 | | alanine racemase [Clostridium difficile 630] | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, Alanine racemase, GLYCEROL | | Authors: | Asojo, O.A. | | Deposit date: | 2013-07-25 | | Release date: | 2014-06-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630.
Acta Crystallogr.,Sect.D, 70, 2014
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4LUT
 | | alanine racemase [Clostridium difficile 630] complex with cycloserine | | Descriptor: | Alanine racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | Authors: | Asojo, O.A. | | Deposit date: | 2013-07-25 | | Release date: | 2014-06-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630.
Acta Crystallogr.,Sect.D, 70, 2014
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4LUY
 | | Crystal structure of CdALR mutant K 271 T | | Descriptor: | Alanine racemase | | Authors: | Asojo, O.A. | | Deposit date: | 2013-07-25 | | Release date: | 2014-06-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630.
Acta Crystallogr.,Sect.D, 70, 2014
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1VFH
 | | Crystal structure of alanine racemase from D-cycloserine producing Streptomyces lavendulae | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, alanine racemase | | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2004-04-13 | | Release date: | 2004-09-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
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1VFS
 | | Crystal structure of D-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae | | Descriptor: | CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase | | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2004-04-19 | | Release date: | 2004-09-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
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3CO8
 | | Crystal structure of alanine racemase from Oenococcus oeni | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2008-03-27 | | Release date: | 2008-04-08 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.F, 69, 2013
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1VFT
 | | Crystal structure of L-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae | | Descriptor: | CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase | | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2004-04-19 | | Release date: | 2004-09-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
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3E6E
 | | Crystal structure of Alanine racemase from E.faecalis complex with cycloserine | | Descriptor: | Alanine racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | Authors: | Hwang, K.Y, Priyadarshi, A, Lee, E.H, Sung, M.W. | | Deposit date: | 2008-08-15 | | Release date: | 2009-08-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the alanine racemase from Enterococcus faecalis.
Biochim.Biophys.Acta, 1794, 2009
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3E5P
 | | Crystal structure of alanine racemase from E.faecalis | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Alanine racemase, NONAETHYLENE GLYCOL, ... | | Authors: | Hwang, K.Y, Priyadarshi, A, Lee, E.H, Sung, M.W. | | Deposit date: | 2008-08-14 | | Release date: | 2009-08-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the alanine racemase from Enterococcus faecalis.
Biochim.Biophys.Acta, 1794, 2009
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1XFC
 | | The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | LeMagueres, P, Im, H, Ebalunode, J, Strych, U, Benedik, M.J, Briggs, J.M, Kohn, H, Krause, K.L. | | Deposit date: | 2004-09-14 | | Release date: | 2005-08-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site.
Biochemistry, 44, 2005
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1XQL
 | | Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase | | Descriptor: | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D. | | Deposit date: | 2004-10-12 | | Release date: | 2005-01-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase
Biochemistry, 44, 2005
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1XQK
 | | Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase | | Descriptor: | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Alanine racemase | | Authors: | Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D. | | Deposit date: | 2004-10-12 | | Release date: | 2005-01-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase
Biochemistry, 44, 2005
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3HA1
 | | Alanine racemase from Bacillus Anthracis (Ames) | | Descriptor: | ACETATE ION, Alanine racemase, CHLORIDE ION | | Authors: | Counago, R.M, Davlieva, M, Strych, U, Hill, R.E, Krause, K.L. | | Deposit date: | 2009-04-30 | | Release date: | 2009-09-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).
Bmc Struct.Biol., 9, 2009
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3HUR
 | | Crystal structure of alanine racemase from Oenococcus oeni | | Descriptor: | Alanine racemase, SULFATE ION | | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Hu, S, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-06-15 | | Release date: | 2009-07-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of alanine racemase from Oenococcus oeni
To be Published
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3B8V
 | | Crystal structure of Escherichia coli alaine racemase mutant E221K | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | Authors: | Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3B8W
 | | Crystal structure of Escherichia coli alaine racemase mutant E221P | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | Authors: | Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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