3CO8
Crystal structure of alanine racemase from Oenococcus oeni
Summary for 3CO8
| Entry DOI | 10.2210/pdb3co8/pdb |
| Descriptor | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
| Functional Keywords | alanine racemase, protein structure initiative ii, psi-ii, nysgxrc, 11082i, plp, tim barrel, structural genomics, new york sgx research center for structural genomics, isomerase, pyridoxal phosphate |
| Biological source | Oenococcus oeni |
| Total number of polymer chains | 2 |
| Total formula weight | 86387.38 |
| Authors | Palani, K.,Burley, S.K.,Swaminathan, S.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2008-03-27, release date: 2008-04-08, Last modification date: 2025-03-26) |
| Primary citation | Palani, K.,Burley, S.K.,Swaminathan, S. Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate. Acta Crystallogr.,Sect.F, 69:15-19, 2013 Cited by PubMed Abstract: The crystal structure of alanine racemase from Oenococcus oeni has been determined at 1.7 Å resolution using the single-wavelength anomalous dispersion (SAD) method and selenium-labelled protein. The protein exists as a symmetric dimer in the crystal, with both protomers contributing to the two active sites. Pyridoxal 5'-phosphate, a cofactor, is bound to each monomer and forms a Schiff base with Lys39. Structural comparison of alanine racemase from O. oeni (Alr) with homologous family members revealed similar domain organization and cofactor binding. PubMed: 23295479DOI: 10.1107/S1744309112047276 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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