6SCZ
Mycobacterium tuberculosis alanine racemase inhibited by DCS
Summary for 6SCZ
Entry DOI | 10.2210/pdb6scz/pdb |
Descriptor | Alanine racemase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (11 entities in total) |
Functional Keywords | enzyme, alanine racemase, peptidoglycan biosynthesis, isomerase |
Biological source | Mycobacterium tuberculosis H37Rv |
Total number of polymer chains | 2 |
Total formula weight | 89556.16 |
Authors | de Chiara, C.,Purkiss, A.,Prosser, G.,Homsak, M.,de Carvalho, L.P.S. (deposition date: 2019-07-26, release date: 2020-04-01, Last modification date: 2024-01-24) |
Primary citation | de Chiara, C.,Homsak, M.,Prosser, G.A.,Douglas, H.L.,Garza-Garcia, A.,Kelly, G.,Purkiss, A.G.,Tate, E.W.,de Carvalho, L.P.S. D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition. Nat.Chem.Biol., 16:686-694, 2020 Cited by PubMed: 32203411DOI: 10.1038/s41589-020-0498-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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