PDB: 86 件ウェブページステータス検索Chemie searchBIRD

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7RW8	AP2 bound to heparin in the closed conformation 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7RW9	AP2 bound to heparin in the bowl conformation 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7P3Y	Homology model of the full-length AP-3 complex in an intermediate open conformation 分子名称: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ... 著者 Schubert, E, Raunser, S. 登録日 2021-07-09 公開日 2021-09-29 最終更新日 2021-12-08 実験手法 ELECTRON MICROSCOPY (10.1 Å) 主引用文献 Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi. J.Biol.Chem., 297, 2021
7P3Z	Homology model of the full-length AP-3 complex in a stretched open conformation 分子名称: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ... 著者 Schubert, E, Raunser, S. 登録日 2021-07-09 公開日 2021-09-29 最終更新日 2021-12-08 実験手法 ELECTRON MICROSCOPY (10.5 Å) 主引用文献 Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi. J.Biol.Chem., 297, 2021
7P3X	Homology model of the full-length AP-3 complex in a compact open conformation 分子名称: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ... 著者 Schubert, E, Raunser, S. 登録日 2021-07-09 公開日 2021-09-29 最終更新日 2021-12-08 実験手法 ELECTRON MICROSCOPY (9.1 Å) 主引用文献 Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi. J.Biol.Chem., 297, 2021
6YAF	AP2 on a membrane containing tyrosine-based cargo peptide 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (9.1 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6YAE	AP2 core in physiological buffer 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6YAH	AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (10.2 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6OXL	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J, Leschziner, A.E, Hollopeter, G. 登録日 2019-05-13 公開日 2019-09-11 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
6OWO	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. 登録日 2019-05-10 公開日 2019-09-11 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
6QH5	AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
6QH6	AP2 clathrin adaptor core with two cargo peptides in open+ conformation 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 最終更新日 2022-12-07 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
6QH7	AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation 分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
6BNT	Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide 分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1 著者 Kikuchi, S, Choi, E, Yu, H. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling. Nat Commun, 10, 2019
6CM9	Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. 登録日 2018-03-03 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.73 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6D84	Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Buffalo, C.Z, Morris, K.L, Hurley, J.H. 登録日 2018-04-25 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.72 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6DFF	Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. 登録日 2018-05-14 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6D83	Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Buffalo, C.Z, Morris, K.L, Hurley, J.H. 登録日 2018-04-25 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6CRI	Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Morris, K.L, Buffalo, C.Z, Hurley, J.H. 登録日 2018-03-18 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
5WRL	Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide 分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1 著者 Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. 登録日 2016-12-02 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.095 Å) 主引用文献 IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
5WRK	Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide 分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION 著者 Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. 登録日 2016-12-02 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
5WRM	Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide 分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1 著者 Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. 登録日 2016-12-02 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.597 Å) 主引用文献 IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
5NZS	The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor 分子名称: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (10.1 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
5NZR	The structure of the COPI coat leaf 分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (9.2 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
5NZU	The structure of the COPI coat linkage II 分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017

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