7RW9

AP2 bound to heparin in the bowl conformation

Summary for 7RW9

Entry DOI	10.2210/pdb7rw9/pdb
EMDB information	24710 24711
Descriptor	AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... (4 entities in total)
Functional Keywords	ap2, clathrin vesicle, endocytosis, lipid-binding, adaptor, membrane, transport
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	204291.84
Authors	Baker, R.W.,Hollopeter, G.,Partlow, E.A. (deposition date: 2021-08-19, release date: 2022-03-30, Last modification date: 2022-04-27)
Primary citation	Partlow, E.A.,Cannon, K.S.,Hollopeter, G.,Baker, R.W. Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29:339-347, 2022 Cited by PubMed: 35347313 DOI: 10.1038/s41594-022-00749-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation