7RW8
| AP2 bound to heparin in the closed conformation | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Baker, R.W, Hollopeter, G, Partlow, E.A. | 登録日 | 2021-08-19 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
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7RW9
| AP2 bound to heparin in the bowl conformation | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Baker, R.W, Hollopeter, G, Partlow, E.A. | 登録日 | 2021-08-19 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
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7P3Y
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7P3Z
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7P3X
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6YAF
| AP2 on a membrane containing tyrosine-based cargo peptide | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | 登録日 | 2020-03-12 | 公開日 | 2020-07-29 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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6YAE
| AP2 core in physiological buffer | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. | 登録日 | 2020-03-12 | 公開日 | 2020-07-29 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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6YAH
| AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | 登録日 | 2020-03-12 | 公開日 | 2020-07-29 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (10.2 Å) | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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6OXL
| CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J, Leschziner, A.E, Hollopeter, G. | 登録日 | 2019-05-13 | 公開日 | 2019-09-11 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
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6OWO
| CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. | 登録日 | 2019-05-10 | 公開日 | 2019-09-11 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
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6QH5
| AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | 登録日 | 2019-01-15 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6QH6
| AP2 clathrin adaptor core with two cargo peptides in open+ conformation | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | 登録日 | 2019-01-15 | 公開日 | 2019-09-04 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6QH7
| AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation | 分子名称: | ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | 登録日 | 2019-01-15 | 公開日 | 2019-09-04 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6BNT
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6CM9
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | 登録日 | 2018-03-03 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6D84
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | 登録日 | 2018-04-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.72 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6DFF
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | 登録日 | 2018-05-14 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6D83
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | 登録日 | 2018-04-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6CRI
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | 登録日 | 2018-03-18 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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5WRL
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.095 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
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5WRK
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
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5WRM
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
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5NZS
| The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor | 分子名称: | ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... | 著者 | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | 登録日 | 2017-05-15 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (10.1 Å) | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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5NZR
| The structure of the COPI coat leaf | 分子名称: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | 著者 | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | 登録日 | 2017-05-15 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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5NZU
| The structure of the COPI coat linkage II | 分子名称: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | 著者 | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | 登録日 | 2017-05-15 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (15 Å) | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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