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7KLZ
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BU of 7klz by Molmil
Structure of SPOP MATH domain in complex with a Geminin peptide
分子名称: Geminin peptide, PHOSPHATE ION, Speckle-type POZ protein
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2020-11-01
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.
Nat Commun, 12, 2021
7LIO
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BU of 7lio by Molmil
X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide
分子名称: Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIQ
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BU of 7liq by Molmil
X-ray structure of SPOP MATH domain (S119A)
分子名称: Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIP
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BU of 7lip by Molmil
X-ray structure of SPOP MATH domain (D140G)
分子名称: SULFATE ION, Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIN
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BU of 7lin by Molmil
X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide
分子名称: SULFATE ION, Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
2CR2
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BU of 2cr2 by Molmil
Solution structure of N-terminal domain of speckle-type POZ protein
分子名称: Speckle-type POZ protein
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of N-terminal domain of speckle-type POZ protein
To be Published
2F1W
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BU of 2f1w by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7
分子名称: CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase 7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F1Y
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BU of 2f1y by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide
分子名称: HAUSP/USP7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F1X
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BU of 2f1x by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a p53 peptide
分子名称: HAUSP/USP7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2FOJ
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BU of 2foj by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 364-367
分子名称: Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide
著者Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
登録日2006-01-13
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
2FOP
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BU of 2fop by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with mdm2 peptide 147-150
分子名称: Ubiquitin carboxyl-terminal hydrolase 7, mdm2 peptide
著者Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
登録日2006-01-13
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
2FOO
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BU of 2foo by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 359-362
分子名称: Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide
著者Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
登録日2006-01-13
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
8DWU
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BU of 8dwu by Molmil
SPOP W22R Form 1
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWV
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BU of 8dwv by Molmil
Full-length wild type SPOP
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWS
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BU of 8dws by Molmil
Full-length E47K SPOP
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWT
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BU of 8dwt by Molmil
SPOP W22R Form 2
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
3HU6
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BU of 3hu6 by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
分子名称: Puckered, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-13
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQI
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BU of 3hqi by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
分子名称: PucSBC1, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
2F1Z
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BU of 2f1z by Molmil
Crystal structure of HAUSP
分子名称: Ubiquitin carboxyl-terminal hydrolase 7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
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