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6KNB	PolD-PCNA-DNA (form A) Descriptor: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ... Authors: Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y. Deposit date: 2019-08-05 Release date: 2020-08-05 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy. Bmc Biol., 18, 2020
1W60	NATIVE HUMAN PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. Deposit date: 2004-08-11 Release date: 2005-01-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
1AXC	HUMAN PCNA Descriptor: P21/WAF1, PCNA Authors: Gulbis, J.M, Kuriyan, J. Deposit date: 1997-10-14 Release date: 1998-01-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
4RJF	Crystal structure of the human sliding clamp at 2.0 angstrom resolution Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen Authors: Kroker, A.J, Bruning, J.B. Deposit date: 2014-10-09 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.0072 Å) Cite: p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding. Biochemistry, 54, 2015
7BUP	Crystal structure of PCNA from pathogenic yeast Candida albicans Descriptor: Proliferating cell nuclear antigen Authors: sundaram, R, Vasudevan, D. Deposit date: 2020-04-07 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations. Febs Lett., 595, 2021
6O09	Structure of AtPCNA in complex with the PIP motif of ATXR6 Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein Authors: Couture, J.F, Davarinejad, H. Deposit date: 2019-02-15 Release date: 2019-03-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.06 Å) Cite: ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle. J. Mol. Biol., 431, 2019
8Q7I	PCNA from Chaetomium thermophilum in complex with Fen1 peptide Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION Authors: Alphey, M.S, Wolford, C.B, MacNeill, S.A. Deposit date: 2023-08-16 Release date: 2023-12-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
1GE8	PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS Descriptor: PROLIFERATION CELL NUCLEAR ANTIGEN Authors: Matsumiya, S, Ishino, Y, Morikawa, K. Deposit date: 2000-10-18 Release date: 2001-01-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus. Protein Sci., 10, 2001
4HK1	Crystal Structure of PCNA from Drosophila melanogaster Descriptor: Proliferating cell nuclear antigen Authors: Wang, K, Shi, Z.B, Zhou, Z.C. Deposit date: 2012-10-14 Release date: 2013-04-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Structure of PCNA from Drosophila melanogaster. Acta Crystallogr.,Sect.F, 69, 2013
8B8T	Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP Descriptor: DNA ligase 1, Proliferating cell nuclear antigen Authors: Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. Deposit date: 2022-10-05 Release date: 2023-01-11 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
3LX2	Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582 Descriptor: DNA polymerase sliding clamp 2, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 Descriptor: DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
5H0T	Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution Descriptor: DI(HYDROXYETHYL)ETHER, Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P.S, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2016-10-06 Release date: 2016-11-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani. Biochim. Biophys. Acta, 1865, 2017
5IY4	Crystal structure of human PCNA in complex with the PIP box of DVC1 Descriptor: DVC1 PIP box, Proliferating cell nuclear antigen Authors: Jiang, T, Xu, M, Wang, Y. Deposit date: 2016-03-24 Release date: 2016-06-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.945 Å) Cite: Crystal structure of human PCNA in complex with the PIP box of DVC1 Biochem.Biophys.Res.Commun., 474, 2016
3F1W	Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis Descriptor: Proliferating cell nuclear antigen Authors: Freudenthal, B.D, Ramaswamy, S, Washington, M.T. Deposit date: 2008-10-28 Release date: 2008-12-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.901 Å) Cite: Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis. Biochemistry, 47, 2008
2NTI	Crystal structure of PCNA123 heterotrimer. Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ... Authors: Hlinkova, V, Ling, H. Deposit date: 2006-11-07 Release date: 2007-12-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
1VYM	NATIVE HUMAN PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. Deposit date: 2004-05-03 Release date: 2005-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ	Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D. Deposit date: 2004-04-30 Release date: 2005-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
7EFA	Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen Authors: Nakamura, T, Nakabeppu, Y, Yamagata, Y. Deposit date: 2021-03-21 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
2OD8	Structure of a peptide derived from Cdc9 bound to PCNA Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen Authors: Chapados, B.R, Tainer, J.A. Deposit date: 2006-12-21 Release date: 2007-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res., 35, 2007
8COB	Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide Descriptor: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen Authors: Ariza, A. Deposit date: 2023-02-27 Release date: 2023-04-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.73 Å) Cite: ERCC6L2 mitigates replication stress and promotes centromere stability. Cell Rep, 42, 2023
5HAC	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution Descriptor: Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2015-12-30 Release date: 2016-03-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution To Be Published
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... Authors: Ling, H. Deposit date: 2008-11-26 Release date: 2009-01-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
7EP8	Crystal structure of PCNA from Neurospora crassa Descriptor: Proliferating cell nuclear antigen Authors: Sundaram, R, Vasudevan, D. Deposit date: 2021-04-26 Release date: 2021-06-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA. J.Biol.Chem., 297, 2021
4L60	Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair Descriptor: Proliferating cell nuclear antigen Authors: Washington, T, Boehm, E. Deposit date: 2013-06-11 Release date: 2013-10-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.003 Å) Cite: Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair. Biochemistry, 52, 2013

 

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