PDB: 164 件ウェブページステータス検索Chemie searchBIRD

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5H4J	Crystal structure of Human dUTPase in complex with N-[(1R)-1-[3-(Cyclopentyloxy)-phenyl]-ethyl]-3-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methoxy]-1-propanesulfonamide 分子名称: DIMETHYL SULFOXIDE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ... 著者 Chong, K.T, Miyahara, S, Miyakoshi, H, Fukuoka, M. 登録日 2016-11-01 公開日 2017-11-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy. Mol. Cancer Ther., 17, 2018
5VJY	Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, dUTP pyrophosphatase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-04-20 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri to be published
1MQ7	CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE 著者 Sawaya, M.R, Chan, S, Segelke, B.W, Lekin, T, Heike, K, Cho, U.S, Naranjo, C, Perry, L.J, Yeates, T.O, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) 登録日 2002-09-13 公開日 2002-10-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341, 2004
4WRK	The 3D structure of D95N mutant DUTPase from phage phi11 of S. aureus reveals the molecular details for the coordination of a structural Mg(II) ion 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Bendes, A.A, Leveles, I, Vertessy, B.G. 登録日 2014-10-24 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The 3D structure of D95N mutant DUTPase from phage phi11 of S. aureus reveals the molecular details for the coordination of a structural Mg(II) ion To Be Published
5NZ2	Twist and induce: Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80 dUTPase. D95E mutant from dUTPase 80alpha phage. 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Alite, C, Humphrey, S, Donderis, J, Maiques, E, Ciges-Tomas, J.R, Penades, J.R, Marina, A. 登録日 2017-05-12 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80 alpha dUTPase. Sci Rep, 7, 2017
5NYZ	Twist and induce: Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80 dUTPase. D95E mutant from dUTPase 80alpha phage. 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Alite, C, Humphrey, S, Donderis, J, Maiques, E, Ciges-Tomas, J.R, Penades, J.R, Marina, A. 登録日 2017-05-12 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80 alpha dUTPase. Sci Rep, 7, 2017
7N6S	Crystal Structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from Rickettsia prowazekii str. Madrid E in complex with 2'-deoxyuridine 5'-monophoephate (dUMP) 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-06-09 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from Rickettsia prowazekii str. Madrid E in complex with 2'-deoxyuridine 5'-monophoephate (dUMP) to be published
7N56	Crystal Structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from Rickettsia prowazekii str. Madrid E 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-06-04 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from Rickettsia prowazekii str. Madrid E to be published
4XJC	dCTP deaminase-dUTPase from Bacillus halodurans 分子名称: DI(HYDROXYETHYL)ETHER, Deoxycytidine triphosphate deaminase, MAGNESIUM ION, ... 著者 Oehlenschlaeger, C, Loevgreen, M, Willemoes, M, Harris, P. 登録日 2015-01-08 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides. Appl.Environ.Microbiol., 81, 2015
7BPD	Crystal structural analysis of Swine dUTPase 分子名称: Deoxyuridine triphosphatase 著者 Liang, R, Peng, G.Q. 登録日 2020-03-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Crystal structural analysis of swine dUTPase To Be Published
8HRV	dutpase of helicobacter pylori 26695 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Kumari, K, Gourinath, S. 登録日 2022-12-16 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 dutpase of helicobacter pylori 26695 To Be Published
5Y5P	Crystal structure of the dUTPase of white spot syndrome virus in complex with dU,PPi and Mg2+ 分子名称: 2'-DEOXYURIDINE, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
5Y5Q	Crystal structure of the WSSV dUTPase D88N/R158E mutant in complex with dUTP 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Wsv112 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
4LHR	Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, TETRAETHYLENE GLYCOL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-07-01 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis TO BE PUBLISHED
5Y5O	Crystal structure of the dUTPase of white spot syndrome virus in the apo state 分子名称: Wsv112 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
4GCY	Structure of Mycobacterium tuberculosis dUTPase H21W mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Toth, J, Vertessy, B.G, Leveles, I, Bendes, A. 登録日 2012-07-31 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 RAMD identification of substrate binding pathways to the active site of dUTPase To be Published
4GK6	X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus 分子名称: CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-08-10 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4GV8	DUTPase from phage phi11 of S.aureus: visualization of the species-specific insert 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Leveles, I, Harmat, V, Nemeth, V, Bendes, A, Szabo, J, Kadar, V, Zagyva, I, Rona, G, Toth, J, Vertessy, B.G. 登録日 2012-08-30 公開日 2013-09-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and enzymatic mechanism of a moonlighting dUTPase Acta Crystallogr.,Sect.D, 69, 2013
8QLD	Bacteriophage T5 dUTPase mutant with loop deletion (30-35 aa) 分子名称: CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL, ... 著者 Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S. 登録日 2023-09-19 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions. Int J Mol Sci, 25, 2024
8QKY	Bacteriophage T5 dUTPase 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL 著者 Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S. 登録日 2023-09-18 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions. Int J Mol Sci, 25, 2024
4OOP	Arabidopsis thaliana dUTPase with with magnesium and alpha,beta-imido-dUTP 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION 著者 Inoguchi, N, Bajaj, M, Moriyama, H. 登録日 2014-02-03 公開日 2015-04-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into the mechanism defining substrate affinity in Arabidopsis thaliana dUTPase: the role of tryptophan 93 in ligand orientation. BMC Res Notes, 8, 2015
4OOQ	apo-dUTPase from Arabidopsis thaliana 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, SULFATE ION 著者 Inoguchi, N, Bajaj, M, Moriyama, H. 登録日 2014-02-03 公開日 2015-07-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.004 Å) 主引用文献 Structural insights into the mechanism defining substrate affinity in Arabidopsis thaliana dUTPase: the role of tryptophan 93 in ligand orientation. BMC Res Notes, 8, 2015
3LQW	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica 分子名称: 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-02-10 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica To be Published
3LOJ	Structure of Mycobacterium tuberculosis dUTPase H145A mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Leveles, I, Harmat, V, Pecsi, I, Lopata, A, Vertessy, B.G, Toth, J. 登録日 2010-02-04 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase Nucleic Acids Res., 38, 2010
3MBQ	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, orthorhombic crystal form 分子名称: 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-25 公開日 2010-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, orthorhombic crystal form To be Published

 

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