2JL9
| Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase | Descriptor: | RNA-DIRECTED RNA POLYMERASE | Authors: | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2008-09-05 | Release date: | 2008-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
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1WNE
| Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-31 | Release date: | 2004-08-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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5XE0
| Crystal structure of EV-D68-3Dpol in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein | Authors: | Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. | Deposit date: | 2017-03-30 | Release date: | 2017-06-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
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5Y6Z
| Crystal structure of the coxsackievirus A16 polymerase elongation complex | Descriptor: | GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... | Authors: | Bi, P, Shu, B, Gong, P. | Deposit date: | 2017-08-15 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics Virol Sin, 32, 2017
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3QID
| Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | Descriptor: | GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ... | Authors: | Kim, K.H, Intekhab, A, Lee, J.H. | Deposit date: | 2011-01-27 | Release date: | 2011-12-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J.Gen.Virol., 92, 2011
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1XR6
| Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B | Descriptor: | Genome polyprotein, POTASSIUM ION | Authors: | Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. | Deposit date: | 2004-10-13 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
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1XR7
| Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16 | Descriptor: | Genome polyprotein | Authors: | Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. | Deposit date: | 2004-10-13 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
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1XR5
| Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14 | Descriptor: | Genome polyprotein, SAMARIUM (III) ION | Authors: | Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. | Deposit date: | 2004-10-13 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
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5Y3D
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5ZIU
| Crystal structure of human Entervirus D68 RdRp | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, RdRp | Authors: | Wang, M.L, Zhang, Y, Chen, Y.P, Lu, D.R, Jiang, H, Chen, Y.J, Li, L, Zhang, C.H, Shi, Q.L, Su, D. | Deposit date: | 2018-03-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.147 Å) | Cite: | Crystal structure of human Entervirus D68 RdRp in complex with NADPH To Be Published
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5ZIT
| Crystal structure of human Enterovirus D68 RdRp in complex with NADPH | Descriptor: | DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp | Authors: | Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D. | Deposit date: | 2018-03-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.196 Å) | Cite: | Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 2020
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3SFU
| crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin | Descriptor: | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, K.H, Alam, I. | Deposit date: | 2011-06-14 | Release date: | 2012-05-09 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
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3SFG
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3BSN
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3BSO
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3CDU
| Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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3CDW
| Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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2B43
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3UR0
| Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION | Authors: | Milani, M, Mastrangelo, E, Bolognesi, M. | Deposit date: | 2011-11-21 | Release date: | 2012-05-02 | Last modified: | 2012-05-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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3DDK
| Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase | Descriptor: | RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION | Authors: | Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B. | Deposit date: | 2008-06-05 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases J.Virol., 82, 2008
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3UPF
| Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023 | Descriptor: | 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION | Authors: | Milani, M, Mastrangelo, E, Bolognesi, M. | Deposit date: | 2011-11-18 | Release date: | 2012-05-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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1HHS
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HHT
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI0
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-31 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI1
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-01 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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