PDB: 96 resultsInfo pagesStatus searchChemie searchBIRD

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2EZ0	Crystal structure of the S107A/E148Q/Y445A mutant of EcClC, in complex with a FaB fragment Descriptor: BROMIDE ION, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), ... Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-10 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.54 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
7CQ7	Structure of the human CLCN7-OSTM1 complex with ADP Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. Deposit date: 2020-08-08 Release date: 2020-11-11 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: Structure of the human CLCN7-OSTM1 complex with ADP To Be Published
8HVT	Structure of the human CLC-7/Ostm1 complex reveals a novel state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ... Authors: Zhang, Z.X, Chen, L, He, J, She, J. Deposit date: 2022-12-27 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure of the human CLC-7/Ostm1 complex reveals a novel state To Be Published
3Q17	Structure of a slow CLC Cl-/H+ antiporter from a cyanobacterium in Bromide Descriptor: BROMIDE ION, Sll0855 protein Authors: Jayaram, H, Robertson, J.L, Fang, W, Williams, C, Miller, C. Deposit date: 2010-12-16 Release date: 2011-01-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium. Biochemistry, 50, 2011
6QV6	CryoEM structure of the human ClC-1 chloride channel, membrane domain Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.63 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
7RSB	CLC-ec1 at pH 4.5 100 mM NaGluconate Turn Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-11 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7BXU	CLC-7/Ostm1 membrane protein complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1 Authors: Zhang, S.S, Yang, M.J. Deposit date: 2020-04-20 Release date: 2020-09-16 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular insights into the human CLC-7/Ostm1 transporter. Sci Adv, 6, 2020
7RP5	CLC-ec1 at pH 4.5 100mM Cl Turn Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-03 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.72 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RO0	CLC-ec1 at pH 7.5 100 mM NaGluconate Swap Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-07-30 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
5TQQ	Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation Descriptor: Chloride channel protein, Monoclonal antibody, Fab fragment, ... Authors: Park, E, MacKinnon, R. Deposit date: 2016-10-24 Release date: 2017-01-04 Last modified: 2019-11-20 Method: ELECTRON MICROSCOPY (3.76 Å) Cite: Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature, 541, 2017
7RP6	CLC-ec1 at pH 4.5 100 mM NaGluconate Swap Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-03 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7XF5	Full length human CLC-2 channel in apo state Descriptor: Chloride channel protein 2 Authors: Wang, L. Deposit date: 2022-04-01 Release date: 2023-05-03 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
5TR1	Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation Descriptor: CHOLESTEROL HEMISUCCINATE, Chloride channel protein, Monoclonal antibody, ... Authors: Park, E, MacKinnon, R. Deposit date: 2016-10-25 Release date: 2017-01-11 Last modified: 2019-11-20 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature, 541, 2017
7RQ7	CLC-ec1 at pH 4.5 100mM Cl TWIST2 Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-05 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
2FEC	Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.967 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
6QVC	CryoEM structure of the human ClC-1 chloride channel, CBS state 1 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
8TA6	Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain Descriptor: Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4.03 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
7N9W	CLC-ec1 pH 4.5 100mM Cl Twist1 Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-06-18 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
6QVU	CryoEM structure of the human ClC-1 chloride channel, low pH Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-05 Release date: 2019-05-08 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QVD	CryoEM structure of the human ClC-1 chloride channel, CBS state 2 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4.34 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QVB	CryoEM structure of the human ClC-1 chloride channel, CBS state 3 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4.34 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019

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