PDB: 96 resultsInfo pagesStatus searchChemie searchBIRD

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6QVD	CryoEM structure of the human ClC-1 chloride channel, CBS state 2 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.34 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QV6	CryoEM structure of the human ClC-1 chloride channel, membrane domain Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.63 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QVB	CryoEM structure of the human ClC-1 chloride channel, CBS state 3 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.34 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QVU	CryoEM structure of the human ClC-1 chloride channel, low pH Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-05 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
6QVC	CryoEM structure of the human ClC-1 chloride channel, CBS state 1 Descriptor: Chloride channel protein 1 Authors: Wang, K.T, Gourdon, P.E, Zhou, Z.H. Deposit date: 2019-03-01 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structure of the human ClC-1 chloride channel. Plos Biol., 17, 2019
8TA5	Title: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with asymmetric C-terminal Descriptor: Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
8TA4	Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with symmetric C-terminal Descriptor: CHLORIDE ION, Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
8TA2	Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42 Descriptor: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.74 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
8TA6	Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain Descriptor: Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4.03 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
8TA3	Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin Descriptor: CHLORIDE ION, Chloride channel protein 2 Authors: Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. Deposit date: 2023-06-26 Release date: 2024-01-31 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
6AD8	Crystal structure of the E148D mutant CLC-ec1 in 50 mM bromide Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
6ADB	Crystal structure of the E148N mutant CLC-ec1 in 20mM bromide Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.692 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
6AD7	Crystal structure of the E148D mutant CLC-ec1 in 20 mM bromide Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
6ADC	Crystal structure of the E148A mutant CLC-ec1 in the presence of 50mM bromoacetate Descriptor: H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, heavy chain, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.055 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
6ADA	Crystal structure of the E148D mutant CLC-ec1 in 200mM bromide Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.153 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
7RP6	CLC-ec1 at pH 4.5 100 mM NaGluconate Swap Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-03 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RQ7	CLC-ec1 at pH 4.5 100mM Cl TWIST2 Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-05 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RP5	CLC-ec1 at pH 4.5 100mM Cl Turn Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-03 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.72 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RSB	CLC-ec1 at pH 4.5 100 mM NaGluconate Turn Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-08-11 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RO0	CLC-ec1 at pH 7.5 100 mM NaGluconate Swap Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-07-30 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
7RNX	CLC-ec1 at pH 7.5 100mM Cl Swap Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Boudker, O, Accardi, A. Deposit date: 2021-07-30 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Structural basis of common gate activation in CLC transporters To Be Published
2FEC	Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.967 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
2EXW	Crystal structure of a EcClC-Fab complex in the absence of bound ions Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-09 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
2EZ0	Crystal structure of the S107A/E148Q/Y445A mutant of EcClC, in complex with a FaB fragment Descriptor: BROMIDE ION, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), ... Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-10 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.54 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
2FEE	Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005

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