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3EGX
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BU of 3egx by Molmil
Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22b and bound to the transport signal sequence of the SNARE protein Bet1
Descriptor: 9-residue synthetic peptide from SNARE protein Bet1, Protein transport protein Sec23A, Protein transport protein Sec24A, ...
Authors:Goldberg, J, Mancias, J.D.
Deposit date:2008-09-11
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
Embo J., 27, 2008
3EH1
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BU of 3eh1 by Molmil
Crystal structure of the human COPII-coat protein Sec24b
Descriptor: Protein transport protein Sec24B, ZINC ION
Authors:Goldberg, J, Mancias, J.D.
Deposit date:2008-09-11
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
Embo J., 27, 2008
3FFK
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BU of 3ffk by Molmil
Crystal structure of human Gelsolin domains G1-G3 bound to Actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, actin, ...
Authors:Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D.
Deposit date:2008-12-03
Release date:2009-10-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FFN
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BU of 3ffn by Molmil
Crystal structure of calcium-free human gelsolin
Descriptor: Gelsolin
Authors:Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D.
Deposit date:2008-12-04
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FG7
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BU of 3fg7 by Molmil
The crystal structure of villin domain 6
Descriptor: Villin-1
Authors:Wang, H, Burtnick, L.D, Robinson, R.C.
Deposit date:2008-12-05
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helix-straightening as an activation mechanism in the gelsolin superfamily of actin regulatory proteins
J.Biol.Chem., 284, 2009
3FG6
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BU of 3fg6 by Molmil
Structure of the C-terminus of Adseverin
Descriptor: Adseverin, CALCIUM ION
Authors:Robinson, R.C.
Deposit date:2008-12-05
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.
Proc.Natl.Acad.Sci.USA, 106, 2009
3A5M
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BU of 3a5m by Molmil
Crystal Structure of a Dictyostelium P109I Mg2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3A5L
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BU of 3a5l by Molmil
Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3A5O
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BU of 3a5o by Molmil
Crystal Structure of a Dictyostelium P109I Ca2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3A5N
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BU of 3a5n by Molmil
Crystal Structure of a Dictyostelium P109A Ca2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3TU5
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BU of 3tu5 by Molmil
Actin complex with Gelsolin Segment 1 fused to Cobl segment
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Kudryashov, D.S, Sawaya, M.R, Durer, Z.A.O.
Deposit date:2011-09-15
Release date:2012-09-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural States and dynamics of the d-loop in actin.
Biophys.J., 103, 2012
2LLF
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BU of 2llf by Molmil
Sixth Gelsolin-like domain of villin in 5 mM CaCl2
Descriptor: Villin-1
Authors:Pfaff, D.A, Brockerman, J, Fedechkin, S, Burns, L, Zhang, F, Mcknight, C, Smirnov, S.L.
Deposit date:2011-11-07
Release date:2012-11-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Gelsolin-like activation of villin: calcium sensitivity of the long helix in domain 6.
Biochemistry, 52, 2013
4BZI
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BU of 4bzi by Molmil
The structure of the COPII coat assembled on membranes
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SAR1P, ...
Authors:Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G.
Deposit date:2013-07-26
Release date:2013-09-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (23 Å)
Cite:The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes
Elife, 2, 2013
4CBU
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BU of 4cbu by Molmil
Crystal structure of Plasmodium falciparum actin I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-1, CALCIUM ION, ...
Authors:Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I.
Deposit date:2013-10-16
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4CBW
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BU of 4cbw by Molmil
Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin
Descriptor: 1,4-DIETHYLENE DIOXIDE, ACTIN, ALPHA SKELETAL MUSCLE, ...
Authors:Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I.
Deposit date:2013-10-17
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4CBX
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BU of 4cbx by Molmil
Crystal structure of Plasmodium berghei actin II
Descriptor: ACTIN-2, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I.
Deposit date:2013-10-17
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4PKI
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BU of 4pki by Molmil
Complex of ATP-actin With the C-terminal Actin-Binding Domain of Tropomodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rao, J.N, Dominguez, R.
Deposit date:2014-05-14
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014
4PKG
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BU of 4pkg by Molmil
Complex of ATP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rao, J.N, Dominguez, R.
Deposit date:2014-05-14
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014
4PKH
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BU of 4pkh by Molmil
Complex of ADP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rao, J.N, Dominguez, R.
Deposit date:2014-05-14
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014
4S10
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BU of 4s10 by Molmil
Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
Descriptor: CALCIUM ION, GELSOLIN NANOBODY, Gelsolin
Authors:Wongsantichon, J, Robinson, R.C, Gettemans, J.
Deposit date:2015-01-07
Release date:2015-06-03
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Hum.Mol.Genet., 24, 2015
4Z94
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BU of 4z94 by Molmil
Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2015-04-09
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
5A1K
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BU of 5a1k by Molmil
Crystal structure of calcium-free human adseverin domains A1-A3
Descriptor: ADSEVERIN
Authors:Chumnarnsilpa, S, Robinson, R.C, Grimes, J.M, Leyrat, C.
Deposit date:2015-04-30
Release date:2015-09-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Calcium-Controlled Conformational Choreography in the N-Terminal Half of Adseverin.
Nat.Commun., 6, 2015
5A1M
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BU of 5a1m by Molmil
Crystal structure of calcium-bound human adseverin domain A3
Descriptor: ADSEVERIN, CALCIUM ION
Authors:Chumnarnsilpa, S, Robinson, R.C, Grimes, J.M, Leyrat, C.
Deposit date:2015-05-01
Release date:2015-09-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Calcium-Controlled Conformational Choreography in the N-Terminal Half of Adseverin.
Nat.Commun., 6, 2015
5FAF
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BU of 5faf by Molmil
N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Boni, F, Milani, M, Ricagno, s, Bolognesi, M, de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
5FAE
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BU of 5fae by Molmil
N184K pathological variant of gelsolin domain 2 (trigonal form)
Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Boni, F, Milani, M, Ricagno, S, Bolognesi, M, de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016

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