PDB: 257 件ウェブページステータス検索Chemie searchBIRD

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8OKX	Structure of cGAS in complex with SPSB3-ELOBC 分子名称: Cyclic GMP-AMP synthase, Elongin-B, Elongin-C, ... 著者 Xu, P.B, Ablasser, A. 登録日 2023-03-29 公開日 2024-02-14 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.51 Å) 主引用文献 The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation. Nature, 627, 2024
8OL1	cGAS-Nucleosome in complex with SPSB3-ELOBC (composite structure) 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Elongin-B, ... 著者 Xu, P.B, Ablasser, A. 登録日 2023-03-29 公開日 2024-02-14 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation. Nature, 627, 2024
8VK4	Structure of mouse RyR1 in complex with S100A1 (high-Ca2+/CFF/ATP dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-08 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. To Be Published
8DTZ	Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Murayama, T, Samso, M. 登録日 2022-07-26 公開日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions To Be Published
8DTY	Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Murayama, T, Samso, M. 登録日 2022-07-26 公開日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions To Be Published
8PD6	Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase TRIM58, ... 著者 Renatus, M, Hoegenauer, K, Schroeder, M. 登録日 2023-06-11 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. Acs Med.Chem.Lett., 14, 2023
8PD4	Crystal structure of TRIM58 PRY-SPRY domain 分子名称: E3 ubiquitin-protein ligase TRIM58 著者 Renatus, M, Schroeder, M. 登録日 2023-06-11 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.714 Å) 主引用文献 Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. Acs Med.Chem.Lett., 14, 2023
8DVV	Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Iyer, K.A, Hu, Y, Murayama, T, Samso, M. 登録日 2022-07-29 公開日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions To Be Published
8VK3	Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Protein S100A1, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-08 公開日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1 To Be Published
8VJK	Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-07 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. To Be Published
8VJJ	Structure of mouse RyR1 (EGTA-only dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-07 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.53 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. To Be Published
8R5C	Crystal structure of human TRIM7 PRYSPRY domain bound to (2-(1-oxoisoindolin-2-yl)-3-phenylpropanoyl)-L-glutamine 分子名称: (2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acid, 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM7, ... 著者 Munoz Sosa, C.J, Kraemer, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-11-16 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of human TRIM7 PRYSPRY domain To Be Published
8R5D	Crystal structure of human TRIM7 PRYSPRY domain 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM7, MALONIC ACID 著者 Munoz Sosa, C.J, Kraemer, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-11-16 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human TRIM7 PRYSPRY domain To Be Published
8R5B	Crystal structure of human TRIM7 PRYSPRY domain bound to (3-phenoxybenzoyl)-L-glutamine 分子名称: (2~{S})-5-azanyl-5-oxidanylidene-2-[(3-phenoxyphenyl)carbonylamino]pentanoic acid, ACETIC ACID, E3 ubiquitin-protein ligase TRIM7 著者 Munoz Sosa, C.J, Kraemer, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-11-16 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of human TRIM7 PRYSPRY domain bound to (3-phenoxybenzoyl)-L-glutamine To Be Published
8UXC	Structure of PKA phosphorylated human RyR2-R420Q in the primed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXE	Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXG	Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXH	Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXF	Structure of PKA phosphorylated human RyR2-R420W in the primed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXL	Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXI	Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXM	Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8G7U	Cryo-EM structure of RNP end 2 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published
8G7T	Cryo-EM structure of RNP end 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published
8G7V	Cryo-EM structure of RNP inter 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published

 

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