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8IZN
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Structural study of Interferon-induced, double-stranded RNA-activated protein kinase (PKR) and Non-structural protein 1 (NS1) complex
分子名称: Interferon-induced, double-stranded RNA-activated protein kinase, Non-structural protein 1
著者Han, C.W, Kim, H.J.
登録日2023-04-07
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (6.67 Å)
主引用文献Structure of PKR and NS1 complex
To Be Published
7RCH
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BU of 7rch by Molmil
Crystal structure of NS1-ED of Vietnam influenza A virus in complex with the p85-beta-iSH2 domain of human PI3K
分子名称: Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta
著者Kim, I, Zhao, B, Li, P, Cho, J.H.
登録日2021-07-07
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus.
Nat Commun, 13, 2022
6ZLC
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BU of 6zlc by Molmil
Non-specific dsRNA recognition by wildtype H7N1 RNA-binding domain
分子名称: NITRATE ION, Non-structural protein 1, RNA (5'-R(*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*U)-3'), ...
著者Coste, F, Wacquiez, A, Marc, D, Castaing, B.
登録日2020-06-30
公開日2020-10-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6SX2
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BU of 6sx2 by Molmil
dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain
分子名称: 1,2-ETHANEDIOL, Non-structural protein 1, RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3')
著者Coste, F, Wacquiez, A, Marc, D, Castaing, B.
登録日2019-09-24
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6SX0
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Specific dsRNA recognition by wild type H7N1 NS1 RNA-binding domain
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Non-structural protein 1, ...
著者Coste, F, Wacquiez, A, Marc, D, Castaing, B.
登録日2019-09-24
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6SW8
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BU of 6sw8 by Molmil
Crystal structure of the NS1 (H7N1) RNA-binding domain
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural protein 1
著者Coste, F, Wacquiez, A, Marc, D, Castaing, B.
登録日2019-09-20
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.933 Å)
主引用文献Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6U28
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BU of 6u28 by Molmil
Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K
分子名称: Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta
著者Cho, J.H, Zhao, B, Savage, N, Li, P.
登録日2019-08-19
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OX7
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The complex of 1918 NS1-ED and the iSH2 domain of the human p85beta subunit of PI3K
分子名称: Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta
著者Shen, Q, Zhao, B, Li, P, Cho, J.H.
登録日2019-05-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OQE
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X-ray structure of H6N6-NS1 delta(80-84) R38A K41A mutant
分子名称: Non-structural protein 1
著者Mitra, S, Kumar, D, Hu, L, Prasad, B.V.V.
登録日2019-04-26
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.899 Å)
主引用文献Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity.
J.Virol., 93, 2019
6O01
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BU of 6o01 by Molmil
X-ray structure of H5N1-NS1 R38A K41A G71E mutant
分子名称: Non-structural protein 1
著者Mitra, S, Kumar, D, Hu, L, Prasad, B.V.V.
登録日2019-02-14
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity.
J.Virol., 93, 2019
6NU0
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BU of 6nu0 by Molmil
Solution NMR structure of 1918 NS1 effector domain
分子名称: Non-structural protein 1
著者Shen, Q, Cho, J.H.
登録日2019-01-30
公開日2020-01-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus.
Biochem.Biophys.Res.Commun., 518, 2019
6NRL
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BU of 6nrl by Molmil
X-ray structure of H6N6-NS1 delta(80-84) R38A K41A E71G mutant
分子名称: Non-structural protein 1
著者Mitra, S, Kumar, D, Hu, L, Prasad, B.V.V.
登録日2019-01-23
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity.
J.Virol., 93, 2019
6E5U
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BU of 6e5u by Molmil
Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein
分子名称: NTF2-related export protein 1, Non-structural protein 1, Nuclear RNA export factor 1
著者Xie, Y, Ren, Y.
登録日2018-07-23
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Nat Microbiol, 4, 2019
6DGK
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BU of 6dgk by Molmil
Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus
分子名称: Non-structural protein 1
著者Kleinpeter, A.B, Green, T.J, Petit, C.M.
登録日2018-05-17
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.
J. Biol. Chem., 293, 2018
5NT1
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BU of 5nt1 by Molmil
Complex of influenza A NS1 effector domain with TRIM25 coiled coil
分子名称: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
著者Koliopoulos, M.G, Rittinger, K.
登録日2017-04-27
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
5NT2
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Complex of influenza A NS1 with TRIM25 coiled coil domain
分子名称: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
著者Koliopoulos, M.G, Rittinger, K.
登録日2017-04-27
公開日2018-05-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.259 Å)
主引用文献Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
5H5N
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BU of 5h5n by Molmil
The crystal structure of the NS1 (H17N10) RNA-binding domain
分子名称: Non-structural protein 1
著者Zhao, X, Qi, J, Xiao, H, Gao, G.F.
登録日2016-11-08
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The NS1 gene from bat-derived influenza-like virus H17N10 can be rescued in influenza A PR8 backbone
J.Gen.Virol., 97, 2016
2N74
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BU of 2n74 by Molmil
Solution Structure of the RNA-Binding domain of non-structural protein 1 from the 1918 H1N1 influenza virus
分子名称: Non-structural protein 1
著者Jureka, A.S, Kleinpeter, A.B, Cornilescu, G, Cornilescu, C.C, Schwieters, C.D, Petit, C.M.
登録日2015-09-03
公開日2015-09-30
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Structure, 23, 2015
5BXZ
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BU of 5bxz by Molmil
H17 Bat Influenza NS1 RNA Binding Domain
分子名称: Non-structural protein 1
著者Kerry, P.S, Hale, B.G.
登録日2015-06-09
公開日2015-08-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.
J.Virol., 89, 2015
5BY1
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BU of 5by1 by Molmil
H18 Bat Influenza NS1 RNA Binding Domain
分子名称: DI(HYDROXYETHYL)ETHER, Non-structural protein 1, PENTAETHYLENE GLYCOL
著者Kerry, P.S, Hale, B.G.
登録日2015-06-09
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.
J.Virol., 89, 2015
4OPH
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BU of 4oph by Molmil
X-ray structure of full-length H6N6 NS1
分子名称: Nonstructural protein 1
著者Carrillo, B, Choi, J.M, Bornholdt, Z.A, Sankaran, S, Rice, A.P, Prasad, B.V.V.
登録日2014-02-05
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.158 Å)
主引用文献The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
J.Virol., 88, 2014
4OPA
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BU of 4opa by Molmil
X-ray structure of H6N6-NS1 delta(80-84) mutant
分子名称: Nonstructural protein 1
著者Carrillo, B.
登録日2014-02-05
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
J.Virol., 88, 2014
3RVC
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BU of 3rvc by Molmil
Effector domain of NS1 from influenza A/PR/8/34 containing a W187A mutation
分子名称: Non-structural protein 1
著者Kerry, P.S, Long, E, Taylor, M.A, Russell, R.J.M.
登録日2011-05-06
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conservation of a crystallographic interface suggests a role for beta-sheet augmentation in influenza virus NS1 multifunctionality.
Acta Crystallogr.,Sect.F, 67, 2011
3P39
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BU of 3p39 by Molmil
Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1
著者Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P31
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Crystal structure of the NS1 effector domain from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1, THIOCYANATE ION
著者Chen, S, Xiao, Y.B, Ponnusamy, R, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published

 

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