4A8D
 
 | | DegP dodecamer with bound OMP | | Descriptor: | OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP | | Authors: | Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | | Deposit date: | 2011-11-20 | | Release date: | 2012-01-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (28 Å) | | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
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3ZRT
 | | Crystal structure of human PSD-95 PDZ1-2 | | Descriptor: | DISKS LARGE HOMOLOG 4 | | Authors: | Sorensen, P.L, Kastrup, J.S, Gajhede, M. | | Deposit date: | 2011-06-19 | | Release date: | 2012-03-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.398 Å) | | Cite: | A High-Affinity, Dimeric Inhibitor of Psd-95 Bivalently Interacts with Pdz1-2 and Protects Against Ischemic Brain Damage.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3AXA
 | | Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3 | | Descriptor: | Afadin, Nectin-3 | | Authors: | Fujiwara, Y, Goda, N, Narita, H, Satomura, K, Nakagawa, A, Sakisaka, T, Suzuki, M, Hiroaki, H. | | Deposit date: | 2011-03-31 | | Release date: | 2012-04-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.
Protein Sci., 24, 2015
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2LOB
 | | PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand) | | Descriptor: | Cystic fibrosis transmembrane conductance regulator, Golgi-associated PDZ and coiled-coil motif-containing protein | | Authors: | Piserchio, A, Fellows, A, Madden, D.R, Mierke, D.F. | | Deposit date: | 2012-01-20 | | Release date: | 2012-06-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics.
Biochemistry, 44, 2005
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3SUZ
 | | Crystal structure of Rat Mint2 PPC | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2 | | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | | Deposit date: | 2011-07-11 | | Release date: | 2012-07-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
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3TMH
 | | Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1 | | Descriptor: | A-kinase anchor protein 10, mitochondrial, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, ... | | Authors: | Sarma, G.N, Phan, R.H, Sankaran, B, Taylor, S.S. | | Deposit date: | 2011-08-31 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published
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4AMH
 | | Influence of circular permutation on the folding pathway of a PDZ domain | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DISKS LARGE HOMOLOG 1, GLYCEROL | | Authors: | Hultqvist, G, Punekar, A.S, Chi, C.N, Selmer, M, Gianni, S, Jemth, P. | | Deposit date: | 2012-03-10 | | Release date: | 2012-12-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Tolerance of Protein Folding to a Circular Permutation in a Pdz Domain
Plos One, 7, 2012
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3SFJ
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4G69
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4E35
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4E34
 | | Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide | | Descriptor: | GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ... | | Authors: | Amacher, J.F, Beck, T, Madden, D.R. | | Deposit date: | 2012-03-09 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.395 Å) | | Cite: | Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
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4E3B
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4F8K
 | | Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1 | | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor | | Authors: | Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P. | | Deposit date: | 2012-05-17 | | Release date: | 2013-02-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1.
Plos One, 8, 2013
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4GVD
 | | Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide | | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | | Deposit date: | 2012-08-30 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
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4GVC
 | | Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide | | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | | Deposit date: | 2012-08-30 | | Release date: | 2013-03-13 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
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3VQF
 | | Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein | | Descriptor: | E3 ubiquitin-protein ligase LNX | | Authors: | Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. | | Deposit date: | 2012-03-22 | | Release date: | 2013-03-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.199 Å) | | Cite: | Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
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3VQG
 | | Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein | | Descriptor: | C-terminal peptide from Immunoglobulin superfamily member 5, E3 ubiquitin-protein ligase LNX, SULFATE ION | | Authors: | Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. | | Deposit date: | 2012-03-23 | | Release date: | 2013-03-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
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4H11
 | | Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy | | Descriptor: | ACETATE ION, Disks large homolog 2, SULFATE ION | | Authors: | Fiorentini, M, Kastrup, J.S, Gajhede, M. | | Deposit date: | 2012-09-10 | | Release date: | 2013-04-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy.
Acta Crystallogr.,Sect.D, 69, 2013
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2M0T
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2M0U
 | | Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1 | | Descriptor: | C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | | Authors: | Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z. | | Deposit date: | 2012-11-06 | | Release date: | 2013-04-24 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
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2M0V
 | | Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1 | | Descriptor: | C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | | Authors: | Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z. | | Deposit date: | 2012-11-06 | | Release date: | 2013-04-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
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2M3M
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2LUI
 | | Structure of the PICK PDZ domain in complex with the DAT C-terminal | | Descriptor: | PICK1 PDZ DOMAIN FUSED TO THE C10 DAT LIGAND | | Authors: | Erlendsson, S, Rathje, M, Heidarsson, P.O, Poulsen, F.M, Madsen, K.L, Teilum, K, Gether, U. | | Deposit date: | 2012-06-14 | | Release date: | 2013-06-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.
J.Biol.Chem., 289, 2014
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4L8N
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2M10
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