3SFJ

Crystal Structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36 inhibitor peptide

Summary for 3SFJ

• Entry DOI: 10.2210/pdb3sfj/pdb
• Descriptor: Tax1-binding protein 3, decameric peptide iCAL36 (3 entities in total)
• Functional Keywords: pdz:peptide complex, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O14907
• Total number of polymer chains: 4
• Total formula weight: 25440.88

Authors

Amacher, J.F.,Madden, D.R. (deposition date: 2011-06-13, release date: 2012-12-12, Last modification date: 2023-09-13)

• Primary citation: Cushing, P.R.,Vouilleme, L.,Amacher, J.F.,Boisguerin, P.,Madden, D.R.; A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR; To be Published,

Experimental method

X-RAY DIFFRACTION (1.24 Å)