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7KUU
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LsfA from P. aeruginosa, a 1-Cys Prx in Sulfonic acid form
分子名称: Alkyl hydroperoxide reductase C
著者AIeixo-Silva, R.L, Domingos, R.M, Netto, L.E.S.
登録日2020-11-25
公開日2021-12-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of LsfA, a 1-Cys Prx in sulfonic acid form
To Be Published
8HH0
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Peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C)
分子名称: 1-naphthalen-2-ylethanone, Peroxiredoxin
著者Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
登録日2022-11-16
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
8HLA
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Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3))
分子名称: 1-naphthalen-2-ylethanone, Peroxiredoxin
著者Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
登録日2022-11-29
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
7LJ1
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Human Prx1-Srx Decameric Complex
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T.
登録日2021-01-28
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.
Antioxidants (Basel), 10, 2021
8EKW
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Cryo-EM structure of human PRDX4
分子名称: Peroxiredoxin-4
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
6Q5V
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1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus
分子名称: Peroxiredoxin
著者Stroobants, S, Maes, D, Peeters, E, van Molle, I.
登録日2018-12-09
公開日2019-05-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus.
Acta Crystallogr.,Sect.F, 75, 2019
6E0G
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Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
6E0F
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Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
7WEU
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BU of 7weu by Molmil
Crystal structure of Peroxiredoxin I in complex with compound 19-048
分子名称: Peroxiredoxin-1, UNKNOWN LIGAND
著者Zhang, H, Luo, C.
登録日2021-12-24
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
7WET
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Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela
分子名称: (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1
著者Zhang, H, Luo, C.
登録日2021-12-24
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
1N8J
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BU of 1n8j by Molmil
Crystal Structure of AhpC with Active Site Cysteine mutated to Serine (C46S)
分子名称: Alkyl hydroperoxide reductase C22 protein
著者Wood, Z.A, Poole, L.B, Karplus, P.A.
登録日2002-11-20
公開日2003-04-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling
Science, 300, 2003
5UCX
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Structure of S78C Human Peroxiredoxin 3 as three stacked rings
分子名称: Thioredoxin-dependent peroxide reductase, mitochondrial
著者Yewdall, N.A, Gerrard, J.A, Goldstone, G.C.
登録日2016-12-22
公開日2018-01-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Quaternary structure influences the peroxidase activity of peroxiredoxin 3.
Biochem. Biophys. Res. Commun., 497, 2018
5UKA
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BU of 5uka by Molmil
Salmonella typhimurium AhpC E49Q mutant
分子名称: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, POTASSIUM ION, ...
著者Perkins, A, Nelson, K, Parsonage, D, Poole, L, Karplus, P.A.
登録日2017-01-20
公開日2018-01-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
Antioxid.Redox Signal., 28, 2018
4RQX
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BU of 4rqx by Molmil
Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA
分子名称: 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4
著者Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
登録日2014-11-05
公開日2015-04-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.256 Å)
主引用文献Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
2HYX
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BU of 2hyx by Molmil
Structure of the C-terminal domain of DipZ from Mycobacterium tuberculosis
分子名称: Protein dipZ
著者Goldstone, D, Baker, E.N, Metcalf, P, TB Structural Genomics Consortium (TBSGC)
登録日2006-08-08
公開日2007-07-17
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the C-terminal domain of DipZ from Mycobacterium tuberculosis
To be Published
2I81
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Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced
分子名称: 2-Cys Peroxiredoxin
著者Artz, J.D, Qiu, W, Dong, A, Lew, J, Ren, H, Zhao, Y, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2006-08-31
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced
To be published
7E4U
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Crystal structure of Peroxiredoxin-1
分子名称: CALCIUM ION, GLYCEROL, Peroxiredoxin 1
著者Ahmed, S, Mok, Y.K, Jobichen, C.
登録日2021-02-15
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Peroxiredoxin-1
To Be Published
6ITZ
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BU of 6itz by Molmil
Peroxiredoxin from Thermococcus kodakaraensis
分子名称: Peroxiredoxin
著者Nakamura, T, Himiyama, T.
登録日2018-11-27
公開日2019-03-06
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
J.Biochem., 166, 2019
6IU1
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Peroxiredoxin from Pyrococcus horikoshii 0Cys mutant)
分子名称: Peroxiredoxin
著者Nakamura, T, Himiyama, T.
登録日2018-11-27
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
J.Biochem., 166, 2019
6IU0
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Peroxiredoxin from Thermococcus kodakaraensis (0Cys mutant)
分子名称: Peroxiredoxin
著者Nakamura, T, Himiyama, T.
登録日2018-11-27
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
J.Biochem., 166, 2019
6J13
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BU of 6j13 by Molmil
Redox protein from Chlamydomonas reinhardtii
分子名称: 2-cys peroxiredoxin
著者Charoenwattansatien, R, Zinzius, K, Tanaka, H, Hippler, M, Kurisu, G.
登録日2018-12-27
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calcium sensing via EF-hand 4 enables thioredoxin activity in the sensor-responder protein calredoxin in the green algaChlamydomonas reinhardtii.
J.Biol.Chem., 295, 2020
7KJ0
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hyperoxidized human peroxiredoxin 2
分子名称: Peroxiredoxin-2
著者Kean, K.M, Karplus, P.A.
登録日2020-10-25
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
7KJ1
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human peroxiredoxin 2 - C172S mutant
分子名称: Peroxiredoxin-2
著者Kean, K.M, Karplus, P.A.
登録日2020-10-25
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
7KIZ
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reduced human peroxiredoxin 2
分子名称: Peroxiredoxin-2
著者Kean, K.M, Karplus, P.A.
登録日2020-10-25
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
2NVL
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Crystal structure of archaeal peroxiredoxin, thioredoxin peroxidase from Aeropyrum pernix K1 (sulfonic acid form)
分子名称: Probable peroxiredoxin
著者Nakamura, T, Yamamoto, T, Abe, M, Matsumura, H, Hagihara, Y, Goto, T, Yamaguchi, T, Inoue, T.
登録日2006-11-13
公開日2007-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008

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