PDB: 285 件ウェブページステータス検索Chemie searchBIRD

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8S5I	Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction 分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE 著者 McCorvie, T.J, Yue, W.W. 登録日 2024-02-23 公開日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5K	Full-length human cystathionine beta-synthase, basal state, single particle reconstruction 分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE 著者 McCorvie, T.J, Yue, W.W. 登録日 2024-02-23 公開日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
1MEH	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP and MOA bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEI	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and mycophenolic acid bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
8U8Y	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, interface-centered 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-18 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
1ME8	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ... 著者 Prosise, G.L, Wu, J, Luecke, H. 登録日 2002-08-08 公開日 2003-01-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site J.Biol.Chem., 277, 2002
8U7Q	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, octamer-centered 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-15 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U7V	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-15 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U7M	Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-15 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U8O	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, octamer-centered 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-18 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
1ME7	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ... 著者 Prosise, G.L, Wu, J, Luecke, H. 登録日 2002-08-08 公開日 2003-01-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site J.Biol.Chem., 277, 2002
1ME9	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEW	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1NF7	Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide 分子名称: Inosine-5'-monophosphate dehydrogenase 2, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ... 著者 Risal, D, Strickler, M.D, Goldstein, B.M. 登録日 2002-12-13 公開日 2004-01-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structure of Human Inosine Monophosphate Dehydrogenase type II complexed with the MPA/NAD analog C2-MAD To be Published
1NFB	Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD 分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2, ... 著者 Risal, D, Strickler, M.D, Goldstein, B.M. 登録日 2002-12-13 公開日 2004-01-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II To be Published
3PC4	Full length structure of cystathionine beta-synthase from Drosophila in complex with serine 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, CG1753, isoform A, ... 著者 Koutmos, M, Smith, J.L. 登録日 2010-10-21 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
3PC3	Full length structure of cystathionine beta-synthase from Drosophila in complex with aminoacrylate 分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CG1753, isoform A, ... 著者 Koutmos, M, Smith, J.L. 登録日 2010-10-21 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
3PC2	Full length structure of cystathionine beta-synthase from Drosophila 分子名称: CG1753, isoform A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Koutmos, M, Smith, J.L. 登録日 2010-10-21 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
3TSD	Crystal Structure of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis str. Ames complexed with XMP 分子名称: D(-)-TARTARIC ACID, Inosine-5'-monophosphate dehydrogenase, SULFATE ION, ... 著者 Kim, Y, Makowska-Grzyska, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-09-13 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.653 Å) 主引用文献 Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes. Biochemistry, 51, 2012
3TSB	Crystal Structure of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis str. Ames 分子名称: Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION 著者 Kim, Y, Makowska-Grzyska, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-09-12 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.595 Å) 主引用文献 Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes. Biochemistry, 51, 2012
7QEM	bacterial IMPDH chimera 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 著者 Labesse, G, Gelin, M, Gedeon, A, Haouz, A, Munier-Lehmann, H. 登録日 2021-12-03 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Protein Sci., 32, 2023
7QDX	bacterial IMPDH chimera 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION 著者 Labesse, G, Gelin, M, Munier-Lehmann, H, Gedeon, A, Haouz, A. 登録日 2021-11-30 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Protein Sci., 32, 2023
7RES	HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+, OCTAMER-CENTERED 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... 著者 Burrell, A.L, Kollman, J.M. 登録日 2021-07-13 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 IMPDH1 retinal variants control filament architecture to tune allosteric regulation. Nat.Struct.Mol.Biol., 29, 2022
7RER	HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+ 分子名称: INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Burrell, A.L, Kollman, J.M. 登録日 2021-07-13 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 IMPDH1 retinal variants control filament architecture to tune allosteric regulation. Nat.Struct.Mol.Biol., 29, 2022
7RFI	HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, INTERFACE-CENTERED 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... 著者 Burrell, A.L, Kollman, J.M. 登録日 2021-07-14 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 IMPDH1 retinal variants control filament architecture to tune allosteric regulation. Nat.Struct.Mol.Biol., 29, 2022

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