3PJT
| Structure of Pseudomonas fluorescence LapD EAL domain complexed with c-di-GMP, C2221 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cyclic dimeric GMP binding protein | Authors: | Sondermann, H, Navarro, M.V.A.S, Krasteva, P. | Deposit date: | 2010-11-10 | Release date: | 2011-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5154 Å) | Cite: | Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis. Plos Biol., 9, 2011
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3PJU
| Structure of Pseudomonas fluorescence LapD EAL domain complexed with c-di-GMP, P6522 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cyclic dimeric GMP binding protein | Authors: | Sondermann, H, Navarro, M.V.A.S, Krasteva, P. | Deposit date: | 2010-11-10 | Release date: | 2011-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4991 Å) | Cite: | Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis. Plos Biol., 9, 2011
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6IH7
| Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - 3',3'-cGAMP bound form | Descriptor: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, cyclic di nucleotide phoshodiesterase | Authors: | Yadav, M, Pal, K, Sen, U. | Deposit date: | 2018-09-28 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication. Biochem.J., 476, 2019
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6IH1
| Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - c-di-GMP bound form | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, cyclic di nucleotide phoshodiesterase | Authors: | Yadav, M, Pal, K, Sen, U. | Deposit date: | 2018-09-28 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication. Biochem.J., 476, 2019
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6IFQ
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6IJ2
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4KIE
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4LJ3
| Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++ | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Cyclic di-GMP phosphodiesterase YahA, ... | Authors: | Sundriyal, A, Schirmer, T. | Deposit date: | 2013-07-04 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP. J.Biol.Chem., 289, 2014
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3S83
| EAL domain of phosphodiesterase PdeA | Descriptor: | GGDEF family protein, POTASSIUM ION | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-05-27 | Release date: | 2011-06-29 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Crystal structure of EAL domain from Caulobacter crescentus CB15 To be Published
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4LYK
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3HV9
| Crystal structure of FimX EAL domain from Pseudomonas aeruginosa | Descriptor: | GLYCEROL, Protein FimX | Authors: | Navarro, M.V.A.S, De, N, Bae, N, Sondermann, H. | Deposit date: | 2009-06-15 | Release date: | 2009-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Structure, 17, 2009
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3HV8
| Crystal structure of FimX EAL domain from Pseudomonas aeruginosa bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Protein FimX | Authors: | Navarro, M.V.A.S, De, N, Bae, N, Sondermann, H. | Deposit date: | 2009-06-15 | Release date: | 2009-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.445 Å) | Cite: | Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Structure, 17, 2009
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2BAS
| Crystal Structure of the Bacillus subtilis YkuI Protein, with an EAL Domain. | Descriptor: | BETA-MERCAPTOETHANOL, YkuI protein | Authors: | Minasov, G, Brunzelle, J.S, Shuvalova, L, Miller, D.J, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-10-14 | Release date: | 2005-11-29 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crystal structures of YkuI and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains. J.Biol.Chem., 284, 2009
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6PWK
| Vibrio cholerae LapD S helix-GGDEF-EAL (bound to c-di-GMP) | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF and EAL domain-containing protein, MAGNESIUM ION | Authors: | Giglio, K.M, Cooley, R.B, Sondermann, H. | Deposit date: | 2019-07-23 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae. Mbio, 10, 2019
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6PWJ
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4F48
| The X-ray structural of FimXEAL-c-di-GMP-PilZ complexes from Xanthomonas campestris | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative uncharacterized protein, Type IV fimbriae assembly protein | Authors: | Chin, K.-H, Liao, Y.-T, Chou, S.-H. | Deposit date: | 2012-05-10 | Release date: | 2012-11-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural polymorphism of c-di-GMP bound to an EAL domain and in complex with a type II PilZ-domain protein. Acta Crystallogr.,Sect.D, 68, 2012
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2W27
| CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM | Descriptor: | CALCIUM ION, GUANOSINE-5'-MONOPHOSPHATE, YKUI PROTEIN | Authors: | Padavattan, S, AndERSON, W.F, Schirmer, T. | Deposit date: | 2008-10-24 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structures of Ykui and its Complex with Second Messenger C-Di-Gmp Suggests Catalytic Mechanism of Phosphodiester Bond Cleavage by Eal Domains. J.Biol.Chem., 284, 2009
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5XGB
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5XGE
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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5XGD
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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5M3C
| Structure of the hybrid domain (GGDEF-EAL) of PA0575 from Pseudomonas aeruginosa PAO1 at 2.8 Ang. with GTP and Ca2+ bound to the active site of the GGDEF domain | Descriptor: | CALCIUM ION, Diguanylate cyclase, GUANOSINE-5'-TRIPHOSPHATE | Authors: | Giardina, G, Brunotti, P, Cutruzzola, F, Rinaldo, S. | Deposit date: | 2016-10-14 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa. FEBS J., 285, 2018
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4RNF
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4RNH
| PaMorA tandem diguanylate cyclase - phosphodiesterase, c-di-GMP complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Motility regulator | Authors: | Phippen, C.W, Tews, I. | Deposit date: | 2014-10-24 | Release date: | 2014-11-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator. Febs Lett., 588, 2014
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3PJW
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4J40
| Crystal structure of the dual-domain GGDEF-EAL module of FimX from Pseudomonas aeruginosa | Descriptor: | FimX | Authors: | Navarro, M.V, De, N, Bae, N, Wang, Q, Sondermann, H. | Deposit date: | 2013-02-06 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Structure, 17, 2009
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