5M3C

Structure of the hybrid domain (GGDEF-EAL) of PA0575 from Pseudomonas aeruginosa PAO1 at 2.8 Ang. with GTP and Ca2+ bound to the active site of the GGDEF domain

Summary for 5M3C

• Entry DOI: 10.2210/pdb5m3c/pdb
• Descriptor: Diguanylate cyclase, CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: phosphodiesterase, c-di-gmp, cyclic-di-gmp, diguanylate, cyclase, eal, ggdef, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 99412.38

Authors

Giardina, G.,Brunotti, P.,Cutruzzola, F.,Rinaldo, S. (deposition date: 2016-10-14, release date: 2017-12-20, Last modification date: 2024-01-17)

• Primary citation: Mantoni, F.,Paiardini, A.,Brunotti, P.,D'Angelo, C.,Cervoni, L.,Paone, A.,Cappellacci, L.,Petrelli, R.,Ricciutelli, M.,Leoni, L.,Rampioni, G.,Arcovito, A.,Rinaldo, S.,Cutruzzola, F.,Giardina, G.; Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa.; FEBS J., 285:3815-3834, 2018; PubMed: 30106221; DOI: 10.1111/febs.14634

Experimental method

X-RAY DIFFRACTION (2.8 Å)