6PWK

Vibrio cholerae LapD S helix-GGDEF-EAL (bound to c-di-GMP)

Summary for 6PWK

• Entry DOI: 10.2210/pdb6pwk/pdb
• Descriptor: GGDEF and EAL domain-containing protein, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: biofilm formation, cell adhesion, c-di-gmp signaling, receptor, signaling protein
• Biological source: Vibrio cholerae O1 str. 2010EL-1786
• Total number of polymer chains: 2
• Total formula weight: 97460.54

Authors

Giglio, K.M.,Cooley, R.B.,Sondermann, H. (deposition date: 2019-07-23, release date: 2019-10-09, Last modification date: 2023-10-11)

• Primary citation: Kitts, G.,Giglio, K.M.,Zamorano-Sanchez, D.,Park, J.H.,Townsley, L.,Cooley, R.B.,Wucher, B.R.,Klose, K.E.,Nadell, C.D.,Yildiz, F.H.,Sondermann, H.; A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae.; Mbio, 10:-, 2019; PubMed: 31796544; DOI: 10.1128/mBio.02822-19

Experimental method

X-RAY DIFFRACTION (2.61 Å)